Challenges with the differential diagnosis of progressive supranuclear palsy and Parkinson’s disease
- 作者: Magzhanov R.1, Davletova A.1, Ibatullin R.2, Tunik V.2, Idrisova R.2, Bakhtiyarova K.2
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隶属关系:
- Bashkir State Medical University
- Kuvatov Republican Clinical Hospital
- 期: 卷 10, 编号 4 (2016)
- 页面: 58-61
- 栏目: Clinical analysis
- URL: https://journals.rcsi.science/2075-5473/article/view/124698
- DOI: https://doi.org/10.17816/psaic22
- ID: 124698
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全文:
详细
Progressive supranuclear palsy (PSP) is a severe old-age neurodegenerative disease that is characterized by pronounced clinical polymorphism and has different phenotypes. Practical differential diagnosis of PSP and Parkinson’s disease (PD) presents significant challenge, especially in onset of the disease. We report an atypical case of PSP characterized by symmetric levodopa-resistant parkinsonian syndrome, early postural instability, supranuclear oculomotor disorders (vertical gaze palsy), MR signs of midbrain atrophy, and a number of overlapping clinical symptoms similar with the manifestations of PD. A detailed algorithm of differential diagnosis of PSP and PD as well as a more adequate diagnostic formulation are proposed for this and similar cases of neurodegenerative pathology.
作者简介
R. Magzhanov
Bashkir State Medical University
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
Angelika Davletova
Bashkir State Medical University
编辑信件的主要联系方式.
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
R. Ibatullin
Kuvatov Republican Clinical Hospital
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
V. Tunik
Kuvatov Republican Clinical Hospital
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
R. Idrisova
Kuvatov Republican Clinical Hospital
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
K. Bakhtiyarova
Kuvatov Republican Clinical Hospital
Email: angelika7d@mail.ru
俄罗斯联邦, Ufa
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