Intravenous (i.v.) thrombolytic therapy of acute ischemic stroke is highly effective in selected group of patients. The most common complications of systemic thrombolysis are intracerebral haematomas, allergic reactions and acute hypotension. The early reocclusion/rethrombosis of intracranial arteries also may influency the efficacy of thrombolysis. The clinical cases of allergic reactions, acute hypotension and early reocclusion in the first 24 hours after i.v. thrombolysis are described in the article. It is concluded that monitoring of neurological status and haemodynamic parameters during and 24 hours after i.v. thrombolysis are the important factors of good outcome.
The course of the acute period of ischemic stroke after inravenous thrombolysis
- 作者: Domashenko M.1, Maksimova M.1, Loskutnikov M.1, Nikonov A.1, Bryukhov V.1
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隶属关系:
- Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
- 期: 卷 5, 编号 1 (2011)
- 页面: 52-57
- 栏目: Original articles
- URL: https://journals.rcsi.science/2075-5473/article/view/124477
- DOI: https://doi.org/10.17816/psaic313
- ID: 124477
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M. Domashenko
Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
编辑信件的主要联系方式.
Email: platonova@neurology.ru
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M. Maksimova
Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
Email: platonova@neurology.ru
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M. Loskutnikov
Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
Email: platonova@neurology.ru
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A. Nikonov
Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
Email: platonova@neurology.ru
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V. Bryukhov
Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)
Email: platonova@neurology.ru
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参考
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- Adams H. et al. Guidelines for the management of adults with ischemic stroke. Stroke 2007; 38: 1655–1711.
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- Guidelines for Management of Ischaemic Stroke of the European Stroke Organisation, 2008. http://www.eso-stroke.org/recommendations
- Lansberg M.G. et al. Risk factors of symptomatic intracerebral hemorrhage after tPA therapy for acute stroke. Stroke 2007; 38: 2275–2278.
- Wardlaw C., Wardlaw J. Therapeutic thrombolysis for acute ischaemic stroke. BMJ, 2003 (1); 326 (7383): 233–234.
