Triple combination in the treatment of hypertension - the real way to improve blood pressure control
- Authors: Morozova T.E.1, Yudina I.Y.1
-
Affiliations:
- I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
- Issue: Vol 19, No 1 (2017)
- Pages: 8-12
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/94639
- ID: 94639
Cite item
Abstract
Ineffective control of blood pressure in patients with essential arterial hypertension in Russian patients (less than 30% women, 20% less than men) demonstrated in epidemiological studies. The article provides an overview of current capabilities to enhance the effectiveness of the treatment of hypertension using a triple combination antihypertensive therapy and the use of fixed combinations. The advantages of combination antihypertensive therapy, including long-acting dihydropyridine calcium channel blocker amlodipine, thiazide diuretic indapamide, and angiotensin-converting enzyme inhibitors perindopril in various clinical situations. A review of research evidence on the effectiveness and safety of a fixed combination of amlodipine/indapamide/perindopril.
Full Text
##article.viewOnOriginalSite##About the authors
T. E. Morozova
I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Email: temorozova@gmail.com
д-р мед. наук, проф., зав. каф. клинической фармакологии и фармакотерапии ИПО ФГАОУ ВО «Первый МГМУ им. И.М.Сеченова» 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2
I. Yu Yudina
I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Email: klinfarma@mail.ru
канд. мед. наук, доц. каф. клинической фармакологии и фармакотерапии ФГАОУ ВО «Первый МГМУ им И.М.Сеченова» 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2
References
- Global Programme on Evidence for Health Policy: WHO. World Health Report, 2002.
- Чазова И.Е. и др. Распространенность факторов риска сердечно - сосудистых заболеваний в российской популяции больных артериальной гипертонией. Кардиология. 2014; 10: 4-12.
- Оганов Р.Г. и др. Эпидемиология артериальной гипертонии в России. Результаты федерального мониторинга 2003-2010 гг. Кардиоваскулярная терапия и профилактика. 2011; 10 (1): 9-13.
- Ezzati M, Lopez A, Rodgers A et al. Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. Geneva: World Health Organization, 2004.
- Диагностика и лечение артериальной гипертонии. Клинические рекомендации, 2013. http://www.cardioweb.ru/klinicheskie-rekomendatsii
- ESH/ESC Guidelines for the management of arterial hypertension. J Hypertens 2013; 31 (7): 1281-357.
- Mourad J.J, Waeber B, Zannad F et al. Comparison of different therapeutic strategies in hypertension: a low - dose combination of perindopril/indapamide versus a sequential monotherapy or a stepped - care approach. J Hypertens 2004; 22: 2379-86.
- Wald D.S, Law M, Morris J.K et al. Combination therapy vs. monotherapy in reducing blood pressure: meta - analysis on 11 000 participants from 42 trials. Am J Med 2009; 122: 290-300.
- Schafer H.H, Sudano I, Theus G.R et al. Target blood pressure attainment with antihypertensive therapy in Swiss primary care. Blood Press 2012; 21: 211-19.
- Bronsert M.R, Henderson W.G, Valuck R et al. Comparative effectiveness of antihypertensive therapeutic classes and treatment strategies in the initiation of therapy in primary care patients: a distributed ambulatory research in therapeutics network (DARTNet) study. J Am Board Fam Med 2013; 26: 529-38.
- Thoenes M, Neuberger H-R, Volpe M et al. Antihypertensive drug therapy and blood pressure control in men and women: an international perspective. J Hum Hypertens 2010; 24, 336-44.
- Osterberg L, Blaschke T. Adherence to Medication. N Engl J Med 2005; 353: 487-97.
- Egan B.M, Bandyopadhyay D, Shaftman S.R et al. Initial monotherapy and combination therapy and hypertension control the first year. Hypertension 2012; 59 (6): 1124-31.
- Gupta A.K, Arshad S, Poulter N.R. Compliance, safety, and effectiveness of fixed - dose combinations of antihypertensive agents, a meta - analysis. Hypertension 2010; 55: 399-407.
- Burnier et al. Antihypertensive Combination Treatment: State of the Art. Curr Hypertens Rep 2015; 17: 51.
- Toth K. PIANIST Investigators. Antihypertensive efficacy of triple combination plus amlodipine in risk hypertensive patients. Am J Cardiovasc Drugs 2014; 14 (2): 137-45.
- Páll D, Szántó I, Szabó Z. Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR. Clin Drug Investig 2014; 34: 701-8.
- Efficiency of the combined treatment of arterial hypertension in Ukraine: results of the TRIUMF multicenter study M.I.Lutay, on behalf of the TRIUMF multicenter study group. Український кардіологічний журнал 2016; 4: 17-28.
Supplementary files
