Comparative Analysis of the Properties of Hydroxyapatite Powders Prepared by Different Techniques

Resumo

The dependence of the physical and chemical properties of hydroxyapatite powder on its preparation technique was determined. Samples produced from biological raw materials by methods of annealing and demineralization of cattle bones were studied. Hydroxyapatite powder surface was studied by scanning electron microscopy, the particle size distribution histograms and the specific surface area values were obtained. The phase compositions of the studied materials were determined by X-ray phase analysis. The preparation technique for ultra-dispersed hydroxyapatite powder with a controlled particle size and Ca/P ratio closest to the stoichiometric one in human bone tissue was determined. It was shown that hydroxyapatite powders produced by cattle bone demineralization method with 1 and 2 M hydrogen chloride aqueous solutions had the best physical and chemical properties in terms of practical application in medicine. Those powders had the smallest particle sizes and the highest specific surface area values.