Rationale for the use of trospium chloride in the first line of therapy for overactive bladder
- Autores: Danilov V.1,2, Volnykh I.1
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Afiliações:
- Pacific State Medical University
- Far Eastern Federal University
- Edição: Volume 30, Nº 1/2 (2023)
- Páginas: 226-230
- Seção: Urology/nephrology
- URL: https://journals.rcsi.science/2073-4034/article/view/258132
- DOI: https://doi.org/10.18565/pharmateca.2023.1-2.226-230
- ID: 258132
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Resumo
The problem of an overactive bladder has been relevant for the last decades. Currently, drugs from the pharmacological group of M-cholinolytics, which increase the functional capacity of the bladder and reduce the severity of the clinical picture of urination disorders, are considered to be the main tool for the treatment. Moreover, M-anticholinergics with the chemical structure of tertiary amines affect the central nervous system. In this regard, trospium chloride, being a water-soluble quaternary base, has significant advantages in diagnosing the functional state of the central nervous system while prescribing treatment.
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##article.viewOnOriginalSite##Sobre autores
Vadim Danilov
Pacific State Medical University; Far Eastern Federal University
Autor responsável pela correspondência
Email: Vadim_danilov@list.ru
Dr. Sci. (Med.), Urologist, Professor at the Institute of Surgery, Department of Clinical Pharmacology
Rússia, Vladivostok; VladivostokI. Volnykh
Pacific State Medical University
Email: Vadim_danilov@list.ru
Institute of Surgery
Rússia, VladivostokBibliografia
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