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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Pharmateca</journal-id><journal-title-group><journal-title xml:lang="en">Pharmateca</journal-title><trans-title-group xml:lang="ru"><trans-title>Фарматека</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2073-4034</issn><issn publication-format="electronic">2414-9128</issn><publisher><publisher-name xml:lang="en">Bionika Media</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">368189</article-id><article-id pub-id-type="doi">10.18565/pharmateca.2025.9.24-30</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Pulmonology/ENT/ARVI</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Пульмонология/ЛОР/ОРВИ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Bronchial asthma in the elderly: diagnostic features, clinical course, and treatment approaches</article-title><trans-title-group xml:lang="ru"><trans-title>Бронхиальная астма пожилых: особенности диагностики, клинического течения и подходы к лечению</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9928-926X</contrib-id><name-alternatives><name xml:lang="en"><surname>Gaynitdinova</surname><given-names>Viliya V.</given-names></name><name xml:lang="ru"><surname>Гайнитдинова</surname><given-names>Вилия Вилевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Department of Pulmonology, N.V. Sklifosovsky</p></bio><bio xml:lang="ru"><p>доктор медицинских наук, профессор кафедры пульмонологии Института клинической медицины им. Н.В. Склифосовского</p></bio><email>ivv_08@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2334-0801</contrib-id><name-alternatives><name xml:lang="en"><surname>Aleksandrova</surname><given-names>Alena A.</given-names></name><name xml:lang="ru"><surname>Александрова</surname><given-names>Алена Алексеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Pulmonologist</p></bio><bio xml:lang="ru"><p>врач-пульмонолог</p></bio><email>doc.aleksandrovaalena@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-3120-0545</contrib-id><name-alternatives><name xml:lang="en"><surname>Evdokimova</surname><given-names>Svetlana A.</given-names></name><name xml:lang="ru"><surname>Евдокимова</surname><given-names>Светлана Анатольевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Head of the Pulmonology Department</p></bio><bio xml:lang="ru"><p>кандидат медицинских наук, зав. пульмонологическим отделением</p></bio><email>Evdokimovasa@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution></aff><aff><institution xml:lang="ru">Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Central Clinical Hospital with Polyclinic of the Administrative Directorate of the President of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Центральная клиническая больница с поликлиникой Управления делами Президента РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-12-29" publication-format="electronic"><day>29</day><month>12</month><year>2025</year></pub-date><volume>32</volume><issue>9</issue><fpage>24</fpage><lpage>30</lpage><history><date date-type="received" iso-8601-date="2026-01-18"><day>18</day><month>01</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Bionika Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, ООО «Бионика Медиа»</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Bionika Media</copyright-holder><copyright-holder xml:lang="ru">ООО «Бионика Медиа»</copyright-holder></permissions><self-uri xlink:href="https://journals.rcsi.science/2073-4034/article/view/368189">https://journals.rcsi.science/2073-4034/article/view/368189</self-uri><abstract xml:lang="en"><p>Globally, the number of elderly patients is growing. It is expected that by 2050, this age group will account for 17% of the global population. As the number of patients over 65 years of age increases, understanding of disease development and clinical features, treatment approaches, and the issue of patient comorbidity are changing. Bronchial asthma in the elderly remains poorly understood. Determining the exact prevalence of bronchial asthma in the elderly is difficult. However, several studies have shown that the prevalence of bronchial asthma in the elderly ranges from 1.8 to 10.9%, is more common in men, and tends to increase over time. This is primarily due to the lack of universal diagnostic criteria in older adults, comorbidity, immunosenescence, heterogeneity of clinical and functional manifestations of the disease, poor patient perception of symptoms, difficulty conducting functional tests, and the lack of response to standard therapy. Therefore, further study of the characteristics of bronchial asthma in this cohort is necessary to improve diagnosis, treatment, and quality of life in elderly patients.</p></abstract><trans-abstract xml:lang="ru"><p>В мире наблюдается тенденция к росту числа пациентов, относящихся к пожилой возрастной группе. Предполагается, что к 2050 г. она будет составлять 17% от общей численности населения земли. По мере увеличения числа пациентов в возрасте старше 65 лет меняются представления о развитии и клинике заболеваний, подходах к терапии, присоединяется проблема коморбидности пациентов. В настоящее время бронхиальная астма у пожилых остаётся недостаточно изученной. Определить точную распространённость астмы среди пожилых сложно, вместе с тем ряд исследований показал, что распространённость бронхиальной астмы среди пожилых колеблется от 1,8 до 10,9%, чаще встречается у мужчин и имеет тенденцию к увеличению распространённости с течением времени. В первую очередь это связано с отсутствием универсальных критериев для постановки диагноза у лиц старшего возраста, коморбидностью, иммуностарением, с гетерогенностью клинических и функциональных проявлений заболевания, слабым восприятием симптомов самим пациентом, сложностью проведения функциональных тестов и с отсутствием эффекта от стандартной терапии. В связи с этим для усовершенствования диагностики, улучшения лечения, а также для повышения качества жизни пожилых пациентов необходимо дальнейшее изучение особенностей течения астмы у данной когорты пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>bronchial asthma in the elderly</kwd><kwd>comorbidity</kwd><kwd>immunosenescence</kwd><kwd>fixed bronchial obstruction</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>бронхиальная астма пожилых</kwd><kwd>коморбидность</kwd><kwd>иммуностарение</kwd><kwd>фиксированная бронхиальная обструкция</kwd><kwd>лечение</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена без спонсорской поддержки.</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Hanania N.A., King M.J., Braman S.S., et al. 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