Hydrolysis of aralosides from Manchurian aralia to oleanolic acid and its derivatives in subcritical water

O. V. Filonova; A. V. Lekar; S. N. Borisenko; E. V. Vetrova; E. V. Maksimenko; N. I. Borisenko; V. I. Minkin

doi:10.1134/S1990793116070071

Hydrolysis of aralosides from Manchurian aralia to oleanolic acid and its derivatives in subcritical water

作者: Filonova O.V.¹, Lekar A.V.¹, Borisenko S.N.¹, Vetrova E.V.¹, Maksimenko E.V.¹, Borisenko N.I.¹, Minkin V.I.¹
隶属关系:
1. Institute of Physical and Organic Chemistry
期: 卷 10, 编号 7 (2016)
页面: 1085-1091
栏目: Article
URL: https://journals.rcsi.science/1990-7931/article/view/198489
DOI: https://doi.org/10.1134/S1990793116070071
ID: 198489

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A method for preparing oleanolic acid (OA) and its derivatives by the hydrolysis of aralosides from Manchurian aralia in subcritical water has been developed. It has been used for the treatment of the Saparal pharmaceutical preparation at 120–240°C in a static regime. The maximal yield of OA has been obtained at 210°C.