The Statue of Cytokines Therapy in Blood Transfusion Running Cytokine and Blood Transfusion
- Authors: Ali Maleki 1, Sayyadipour F.2, Ahmadi H.3, Soleimani M.4, Saba F.2
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Affiliations:
- Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences
- Department of Medical Laboratory Science, School of paramedical, Kermanshah University of Medical Sciences
- Department of anatomy. Medical school, Tehran University of Medical School
- Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University
- Issue: Vol 13, No 6 (2019)
- Pages: 407-417
- Section: Article
- URL: https://journals.rcsi.science/1990-519X/article/view/213020
- DOI: https://doi.org/10.1134/S1990519X19060051
- ID: 213020
Cite item
Abstract
In order to improve the patient’s condition, the transfusion of blood products is used, however, there are problems with blood transfusion including infections, immune suppression, allergic reactions and anaphylactic shock-related to leukemia and plasma product. Cytokine can now be an appropriate choice to reduce the need for blood transfusion. Various types of cytokines have been studied in human clinical trials and some of them have a substantial function to decrease blood transfusion. In this study, we have investigated the important cytokines involved in reducing cells (Red blood cells and platelets) transfusion. First, we have investigated the cytokines involved in erythropoiesis and thrombopoiesis and covered some clinical studies about them. The second side effects of the administration of these cytokines have been addressed, and finally, we have suggested some recommendations about cytokine therapy.
Keywords
About the authors
Ali Maleki
Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences
Email: Fakhredin.Saba@kums.ac.ir
Iran, Islamic Republic of, Kermanshah
Fatemeh Sayyadipour
Department of Medical Laboratory Science, School of paramedical, Kermanshah University of Medical Sciences
Email: Fakhredin.Saba@kums.ac.ir
Iran, Islamic Republic of, Kermanshah
Hamid Ahmadi
Department of anatomy. Medical school, Tehran University of Medical School
Email: Fakhredin.Saba@kums.ac.ir
Iran, Islamic Republic of, Tehran
Masoud Soleimani
Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University
Email: Fakhredin.Saba@kums.ac.ir
Iran, Islamic Republic of, Tehran
Fakhredin Saba
Department of Medical Laboratory Science, School of paramedical, Kermanshah University of Medical Sciences
Author for correspondence.
Email: Fakhredin.Saba@kums.ac.ir
Iran, Islamic Republic of, Kermanshah