Malignant neoplasms in HIV patients in Russia: the story over a 20-year period

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Abstract

According to the official statistics, by the beginning of 2021, the overall number of registered HIV cases in Russia exceeded 1.1 million. For about 100 000 new HIV-infected patients have been registered annually in Russia recent years. Russia occupies one of the leading places in the incidence of HIV infection, and the growth rate of new HIV cases is not decreasing. HIV-infected patients have higher incidence of malignant neoplasms (MN) in comparison with the overall population and have the highest cancer mortality rates. The problem of HIV-associated malignancies is at the junction of two socially significant issues, and this situation especially taking into account in Russian Federation. The problems of diagnosis and treatment of MN are becoming topical, and it is extremely important to study HIV-associated malignancies epidemiology in the Russian Federation. This will help to create effective algorithms for organizing dispensary observation for HIV infected people, will help to early diagnosis of the disease, timely initiation of treatment and, as a result, will help to achieve the best oncological results.

About the authors

Anastasyia V. Nekrasova

Tsyb Medical Radiological Scientific Center – branch of the National Medical Research Radiological Centre

Author for correspondence.
Email: nekrasova.anastasiya.doc@mail.ru
ORCID iD: 0000-0002-0016-2531

oncologist

Russian Federation, Obninsk

Vadim V. Rassokhin

Pavlov First Saint Petersburg State Medical University

Email: nekrasova.anastasiya.doc@mail.ru
ORCID iD: 0000-0002-1159-0101

D. Sci. (Med.), Prof.

Russian Federation, Saint Petersburg

Natalia A. Falaleeva

Tsyb Medical Radiological Scientific Center – branch of the National Medical Research Radiological Centre

Email: nekrasova.anastasiya.doc@mail.ru
ORCID iD: 0000-0002-0023-4216

D. Sci. (Med.)

Russian Federation, Obninsk

Lyudmila Y. Grivtsova

Tsyb Medical Radiological Scientific Center – branch of the National Medical Research Radiological Centre

Email: nekrasova.anastasiya.doc@mail.ru
ORCID iD: 0000-0001-9103-9688

D. Sci. (Biol.), Cand. Sci. (Med.)

Russian Federation, Obninsk

Denis A. Gusev

Botkin Hospital for Infictuous Diseases

Email: nekrasova.anastasiya.doc@mail.ru

D. Sci. (Med.), Prof.

Russian Federation, Saint Petersburg

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. The ways of transmission of HIV infection in patients with MN.

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3. Fig. 2. The dynamics of the incidence of new MN cases by year (1994–2016).

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4. Fig. 3. The dynamics of the incidence of new cases of HIV-associated tumors/ non-HIV-associated tumors by year.

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5. Fig. 4. Distribution of MN according to stages (n=301*).

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6. Fig. 5. Antiretroviral therapy coverage for HIV-infected patients before MN is registered.

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7. Fig. 6. Viral load – the number of copies of HIV RNA in blood patients with HIV and MN.

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