Squamous cell breast cancer: description of a rare clinical case

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Abstract

Squamous cell carcinoma of the breast is a rare, aggressive tumor with a poor prognosis. To date, due to the low incidence of morbidity, there is no single concept in the complex treatment of this pathology. The article describes the case of a 49-year-old patient after surgical treatment of squamous cell carcinoma of the left breast from 2019 on the anamnesis. A year later after the progression of the disease the patient underwent removal of a chest wall tumor with resection of III–V ribs, allo- and autoplasty, axillary lymphadenectomy on the left. In most cases, the treatment of squamous cell carcinoma of the breast is surgery, but the role of adjuvant chemotherapy, radiation therapy and endocrinotherapy are still unambiguous.

About the authors

Azizzhon D. Zikiryakhodjaev

Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center

Author for correspondence.
Email: hgg_doc@mail.ru
ORCID iD: 0000-0001-7141-2502

D. Sci (Med.)

Russian Federation, Moscow

Shakhnoz G. Khakimova

Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center; Tashkent Pediatric Medical Institute

Email: hgg_doc@mail.ru
ORCID iD: 0000-0002-9491-0413

Cand. Sci. (Med.)

Russian Federation, Moscow; Tashkent, Uzbekistan

Elena A. Rasskazova

Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center

Email: hgg_doc@mail.ru
ORCID iD: 0000-0003-0307-8252

Cand. Sci. (Med.)

Russian Federation, Moscow

Erik K. Saribekian

Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center

Email: hgg_doc@mail.ru
ORCID iD: 0000-0003-0827-7998

D. Sci (Med.)

Russian Federation, Moscow

Dzhanet F. Omarova

Sechenov First Moscow State Medical University (Sechenov University)

Email: hgg_doc@mail.ru
ORCID iD: 0000-0003-1824-6888

Graduate Student

Russian Federation, Moscow

Viktoriia S. Surkova

Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center

Email: hgg_doc@mail.ru
ORCID iD: 0000-0002-2674-0416

pathomorphologist

Russian Federation, Moscow

Gulnoz G. Khakimova

Tashkent Pediatric Medical Institute; Tashkent City branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology

Email: hgg_doc@mail.ru
ORCID iD: 0000-0002-4970-5429

Cand. Sci. (Med.)

Uzbekistan, Tashkent

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Supplementary files

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2. Fig. 1. Macroscopic view of endoprosthesis capsule with the growth of the tumor on the inner surface.

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3. Fig. 2. PET/CT projection: a – axial; b – sagittal. The increased metabolic activity with 18F-FDG is showed in the soft tissues of the left chest wall and in the anterior segments of IV–V ribs on the left.

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4. Fig. 3. Preoperative marking of the patient.

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5. Fig. 4: a – incision; b – the skin of the breast is undermined and elevated.

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6. Fig. 5: a – the thoracodorsal vessels are showed; b – the latissimus muscle flap with cutaneous fat pad.

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7. Fig. 6: a – the removed mass intimately rests on the upper lobe of the lung; b, c – the view after en bloc resection of the ribs and atypical resection of the lung.

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8. Fig. 7: a – the part of the left anterior chest wall with the sections of III–V ribs; b – the growth of tumor in the soft tissues of the anterior chest wall.

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9. Fig. 8: a – The Codubix Ribs are implanted; b – the wound is covered with a thoracodorsal flap; c – the view of the patient on the operating table.

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10. Fig. 9: a – well differentiated squamous cell carcinoma; b – well differentiated squamous cell carcinoma with ingrowth and destruction of bone tissue; c – lymph node metastasis of well differentiated squamous cell carcinoma.

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