Solitary metastasis of colorectal cancer in the left adrenal gland 4 years after surgery on the primary tumor. Case report

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Abstract

Colorectal cancer (CRC) is one of the most common oncological diseases. On average, in 20–25% of cases after radical surgical treatment of CRC, the progression of the disease in the form of metachronous metastases in the liver and lungs, as the most common localization of CRC metastases, is noted in patients. With the advent of new drug treatment strategies for CRC, there is an increase in overall survival, as a result of which CRC metastases in the adrenal glands have become more common than previously thought, and the number of published reports of cases of CRC metastasis in the adrenal glands has increased. In this article, we report a rare clinical observation of metachronous solitary metastasis of CRC to the left adrenal gland 4 years after radical surgical treatment of the primary tumor: the patient underwent radical left-sided adrenalectomy. The period of observation of the patient without signs of progression and relapse of the disease is 6 months (at the time of publication).

About the authors

Marina D. Budurova

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre; Yevdokimov Moscow State University of Medicine and Dentistry

Author for correspondence.
Email: m.budurova@rambler.ru
ORCID iD: 0000-0003-1391-0516

d. sci. (med.)

Russian Federation, Moscow

Vladimir S. Trifanov

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre; Peoples' Friendship University of Russia (RUDN University)

Email: trifan1975@yandex.ru
ORCID iD: 0000-0003-1879-6978

head of the surgical department

Russian Federation, Moscow

Vladimir V. Kopylov

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre

Email: copylow.vladimir@yandex.ru
ORCID iD: 0000-0001-7608-128X

cand. sci. (med.)

Russian Federation, Moscow

Olga S. Kuznetsova

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre

Email: olga-sudalenko@yandex.ru
ORCID iD: 0000-0003-1789-4007

pathologist

Russian Federation, Moscow

Maria A. Chernichenko

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre

Email: mashustic04@mail.ru
ORCID iD: 0000-0002-2427-9232

cand. sci. (med.)

Russian Federation, Moscow

Sergey I. Poluektov

Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre

Email: Poluektovsi@yandex.ru
ORCID iD: 0000-0001-7603-4221

cand. sci. (med.)

Russian Federation, Moscow

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Supplementary files

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1. JATS XML
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2. Fig. 1. CT scan of the chest, abdomen and retroperitoneum, pelvis with intravenous contrast enhancement on July 15, 2022.

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3. Fig. 2. Metastasis of moderately differentiated intestinal adenocarcinoma to the adrenal gland. ×10, hematoxylin-eosin staining.

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