Dynamics of carbohydrate - lipid metabolism and digestive tract microbiocenosis in patients with chronic generalized periodontitis during complex therapy of metabolic syndrome

We detected a directly proportional tendency of increase to the severity of lesions of periodontal tissues depending on the BMI. This is mostly detected in patients with a BMI ≥ 25 kg /m2. 93 patients were selected for examination and treatment to identify the role of periodontitis as a risk factor in the CVC. We studied glycemic and lipid profile, activity of systemic inflammation (C-reactive protein), the activity of oxidative stress in the dynamics before and after treatment (12 weeks).To the standard therapy of periodontitis for the relief of oxidative stress (systemic inflammation) and compensation dysbiosis were added Ubiquinone comp (2 ml/VM - 2 times a week) and probiotics - Simbiolakt-Comp (1 sachet per day). Along with the normalization of the digestive tract biocenosis marked decrease in proinflammatory status and oxidative stress.

biochemical analysis, body mass index, chronic generalized periodontitis, dysbiosis, metabolic syndrome