The impact of defects of dentition in a state of salivation and local immunity of oral cavity in patients with diabetes mellitus type 2


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Abstract

The article presents the indicators of the secretory function of salivary glands and local immunity of mouth cavity in type 2 diabetic patients with edentulous space. In 2013-2014, 93 patients divided into 3 groups depending on the dentition were examined. The first group comprised healthy patients with intact and restored fixed dentures, the second one had healthy patients with edentulous space requiring removable denture, and the third group included type 2 diabetic patients with similar edentulous space. The examination determined background and stimulated secretion of salivary glands and local immunity of the mouth cavity. The study found the decrease in functional activity of salivary glands and metabolic potential of salivary neutrophils in type 2 diabetic patients requiring the orthopedic treatment with removable dentures. The analysis of the functional activity of the local protective factors of the mouth cavity in type 2 diabetic patients enables applying methods of immunocorrection for regulating inflammatory processes in orthopedic treatment with removable denture.

About the authors

Natal’ya Alekseevna Shevkunova

«Izhevsk State Medical Academy» of the Ministry of health of the Russian Federation

Email: shevkunova.natalia@mail.ru
cand. med. sci., assistant professor; Izhevsk State Medical Academy, Departament of orthopedic stomatology 426000, Izhevsk, Russia

I. S Redinov

«Izhevsk State Medical Academy» of the Ministry of health of the Russian Federation

426000, Izhevsk, Russia

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