THE COMPUTER REGISTER STUDY OF FREQUENCY OF CONGENITAL BRAIN MALFORMATIONS IN CHILDREN FROM ECOLOGICALLY VARIOUS AREAS OF BRYANSK REGION

The relevance of congenital malformations (CM) study is due to this pathology increase in the structure of causes of infant mortality, child morbidity and disability, CM cases increase in children both in Russia and in the world. The analysis of frequency and structure of brain congenital malformations in children, depending on technogenic radiation pollution of the Bryansk region living areas has been given in the article. The aim of this work was to study the generalization peculiarities of brain congenital malformations in different groups of children on the basis of regional CM monitoring in the Bryansk region depending on the anthropogenic pollution degree in the living areas by using the computer register. The study basis was data on the brain congenital malformations prevalence among newborns of Bryansk Region according to the official statistical reporting for the period 1999-2014. The study result did not stated statistically significant exceedence of the average values of the CM indicators in children from more radiation-contaminated South-Western territories in comparison with the same data of unpolluted areas. However, the maximum value of the average numbers of anencephaly, microcephaly and encephalocele were registered in the most contaminated districts of the region.

Congenital malformations, teratogenic effect, monitoring, radioactive contamination