Disease as a result of violations of the symbiotic relationship between the host and the microbiota with pathogens
- 作者: Tkachenko E.1, Grinevich V.1, Gubonina I.1, Kravchuk Y.1, Apcel V.1,2, Ivanyuk E.1
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隶属关系:
- Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
- Russian State Pedagogical University named after A.I. Herzen
- 期: 卷 23, 编号 2 (2021)
- 页面: 243-252
- 栏目: Education news
- URL: https://journals.rcsi.science/1682-7392/article/view/58117
- DOI: https://doi.org/10.17816/brmma58117
- ID: 58117
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详细
Recent achievements in many sciences have led to an understanding of the need to form new ideas about the nature of human relationships with the environment and the inner world, his health, the principles of disease formation and their prevention. There has been a transition from a collection of achievements of various sciences to a holistic paradigm that unites a person as an organism and as a person, his inner and surrounding world. It became obvious that this could not be done within the framework of the previous general theories of medicine. To this end, the authors propose a new theory of medicine: "the theory of noospheric-anthropogenic harmony". From the standpoint of this theory, the mechanisms of the relationship of microbiota and pathogens with the protective and acceptive immunity of a healthy and sick person, as well as the mechanisms of microbiota regulation, are considered. The paradigm of dysbiosis as the cause of many diseases and main homeostatic mechanisms that provide symbiotic relationships of microbiota, immunity and its role in the mechanisms of natural tolerance and formation of various disease, such as, autoimmune ones and tumors, require a change in the acceptedtreatment and prevention. A new approach should be based on using a new class of drugs — metabiotics, which in their term influence microbiota.
作者简介
Evgeny Tkachenko
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
编辑信件的主要联系方式.
Email: info@eco-vector.com
doctor of medical sciences, professor
俄罗斯联邦, Saint PetersburgVladimir Grinevich
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: info@eco-vector.com
doctor of medical sciences, professor
俄罗斯联邦, Saint PetersburgIrina Gubonina
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: info@eco-vector.com
candidate of medical sciences, associate professor
俄罗斯联邦, Saint PetersburgYuriy Kravchuk
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: info@eco-vector.com
doctor of medical sciences, associate professor
俄罗斯联邦, Saint PetersburgVasily Apcel
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation; Russian State Pedagogical University named after A.I. Herzen
Email: info@eco-vector.com
ORCID iD: 0000-0001-7658-4856
SPIN 代码: 4978-0785
Scopus 作者 ID: 6507529350
Researcher ID: Е-8190-2019
doctor of medical sciences, professor
俄罗斯联邦, Saint Petersburg; Saint PetersburgElena Ivanyuk
Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation
Email: info@eco-vector.com
candidate of medical sciences
俄罗斯联邦, Saint Petersburg参考
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