Mineral bischofite complexes in medical rehabilitation of patients with chronic generalized periodontitis

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The purpose of the research is to improve the efficiency of restorative treatment of patients with chronic generalized periodontitis based on the inclusion in therapeutic schemes of innovative mineral bishophytic complexes ― gel "Bishophytic" and rinser "Polymineral."

Materials and methods. The study involved 116 patients at the age of 35 to 73 years old suffering from periodontal pathology (mild and moderate chronic generalized periodontitis). They were distributed by simple randomization into 3 groups: the main group included 43 people who received standard treatment in accordance with Russian clinical recommendations for the treatment of periodontitis, 45 minutes later the patients were prescribed some applications with 10% dental gel "Bishophytic" on the gum, in addition, the patients were recommended to use a rinser "Polymineral" for 6 months; the group of comparison included
39 people who received standard treatment and gum applications with 10% "Bishophytic" dental gel; the control group) included 38 people who received only standard treatment.

Results. Inclusion of mineral bishophytic complexes in treatment programs of patients with CGP contributes to significant reduction of inflammatory activity of periodontal tissues: 61.3% (p < 0.01) had the improvement of hygienic and plaque indices in comparison with initial data; 54.6% (р < 0,01) had the improvement after additional use of only gum applications with "Bishophytic" gel; the improvement was 52.2% (р < 0.01) after basic drug therapy. Thus, the improvement of enzymatic processes was by 30.0% (p < 0.01), 26.9% (p < 0.01) and 7.8%; reduction of cytokine activity by 62.8% (p<0.01), 61.1% (p < 0.01) and 40%; the improvement of dental health by 84.0% (p < 0.01), 80.7% (p < 0.01) and 74.5% (p < 0.01) at рkg-ог< 0,05 and рkg-ог<0,01.

Conclusion. Inclusion of innovative mineral bishophytic complexes (gel "Bishophytic" and rinser "Polymineral") in treatment programs of patients with chronic generalized periodontitis contributes to optimization of therapeutic measures: clinical effectiveness in the main group was 93.0%; after usage of dental gel "Bishophytic" (group of comparison) it was 89.7% and after basic therapy (control group) — 81.6%.

作者简介

Agnessa Kaisinova

North Caucasian Federal Scientific and Clinical Centre of Federal Medical-Biological Agency

编辑信件的主要联系方式.
Email: zamoms@skfmba.ru
SPIN 代码: 6552-9684

DSc., Prof.

俄罗斯联邦, Essentuki

Ilya Zelenski

Stavropol State Medical University of the Ministry of Health of the Russian Federation

Email: zamoms@skfmba.ru
SPIN 代码: 4347-0760
俄罗斯联邦, Stavropol

Natalia Efimenko

North Caucasian Federal Scientific and Clinical Centre of Federal Medical-Biological Agency

Email: zamoms@skfmba.ru
ORCID iD: 0000-0001-7005-8927
SPIN 代码: 8041-7520

DSc, Prof.

俄罗斯联邦, Essentuki

Elena Chalaya

North Caucasian Federal Scientific and Clinical Centre of Federal Medical-Biological Agency

Email: zamoms@skfmba.ru
SPIN 代码: 1084-2875

PhD

俄罗斯联邦, Essentuki

参考

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