点阵光热分解技术在早期瘀斑治疗中的应用: 有效治疗方案的制定
- 作者: Shamsutdinova D.S.1, Ponomarenko I.G.2, Ponomarenko G.N.1,2, Platonova A.V.3
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隶属关系:
- Federal Scientific and Aducational Centre of Medical and Social Expertis and Rehabilitation n. a. G.A. Albrecht
- North-Western State Medical University named after I.I. Mechnikov
- Kirov Military Medical Academy
- 期: 卷 24, 编号 5 (2025)
- 页面: 383-390
- 栏目: Original studies
- URL: https://journals.rcsi.science/1681-3456/article/view/354745
- DOI: https://doi.org/10.17816/rjpbr686665
- EDN: https://elibrary.ru/GERGGJ
- ID: 354745
如何引用文章
详细
论证:瘀斑的治疗仍是皮肤病学与美容医学中的重要问题。血红蛋白降解产物(氧合血红蛋白 → 脱氧血红蛋白 → 高铁血红蛋白 → 胆绿素 → 胆红素 → 含铁血黄素)导致的皮肤色素改变会引起患者心理不适,并延长外伤、术后或介入治疗后的康复期。传统疗法(含肝素药膏外用、冷热敷)疗效有限,因此亟需探索物理治疗方法以加快瘀斑消退。
目的:对应用波长为(10 600 nm)、L型脉冲的CO2点阵激光进行光热分解治疗瘀斑的科学依据进行论证,并制定有效的治疗方案。
材料与方法:开展前瞻性比较研究,以评估利用二氧化碳点阵激光光热分解技术进行瘀斑矫正方法的疗效与安全性。纳入25例病程1–5天的创伤后或术后瘀斑患者,并将其分为观察组(激光治疗,n=15)和对照组(传统治疗,n=10)治疗参数:在点阵光热分解模式下,采用CO2激光,L型脉冲(10 600 nm),功率6–8 W,微热治疗区密度400–500点/cm²,单次叠加,脉冲持续时间500–600 μs。通过照片评估、色彩量表及视频皮肤镜进行动态监测。
结果。激光治疗组显示显著改善,瘀斑消退时间缩短40–50%(平均5±1.8天 vs 对照组14±2.3天,p<0.05)。观察到瘀斑颜色加速由青紫色向黄色转变(第3–4天),并且残留色素沉着的风险降低。总体疗效达85%(显著改善)。安全性水平较高:仅20%的患者出现轻度短暂性红斑,并在24小时内自行缓解。
结论:L型脉冲CO2点阵光热分解技术可实现对色素沉着表皮的定向消融并促进淋巴引流,是早期瘀斑治疗的有效手段。优化参数(6–8 W,400–500 MTZ/cm²,500–600 μs,单次叠加)可在避免周围完整组织微热损伤的同时,对血红蛋白降解产物实现可控作用。
作者简介
Diana S. Shamsutdinova
Federal Scientific and Aducational Centre of Medical and Social Expertis and Rehabilitation n. a. G.A. Albrecht
Email: prokt57@mail.ru
ORCID iD: 0009-0007-1759-9995
俄罗斯联邦, Saint Petersburg
Inga G. Ponomarenko
North-Western State Medical University named after I.I. Mechnikov
编辑信件的主要联系方式.
Email: manga-85@mail.ru
ORCID iD: 0000-0001-6550-6940
SPIN 代码: 7930-2463
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, Saint PetersburgGennady N. Ponomarenko
Federal Scientific and Aducational Centre of Medical and Social Expertis and Rehabilitation n. a. G.A. Albrecht; North-Western State Medical University named after I.I. Mechnikov
Email: ponomarenko.gn@gmail.com
ORCID iD: 0000-0001-7853-4473
SPIN 代码: 8234-7005
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, Saint Petersburg; Saint PetersburgAnna V. Platonova
Kirov Military Medical Academy
Email: platonova1105@gmail.com
ORCID iD: 0000-0001-7143-8411
SPIN 代码: 5609-9713
MD, Cand. Sci. (Medicine)
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