Effect of Transcription on the  white  Gene Enhancer Integrated into the Intron

M. M. Erokhin; A. V. Mikhailova; P. G. Georgiev; D. A. Chetverina

doi:10.1134/S1607672919010125

Effect of Transcription on the white Gene Enhancer Integrated into the Intron

作者: Erokhin M.M.¹, Mikhailova A.V.¹, Georgiev P.G.¹, Chetverina D.A.¹
隶属关系:
1. Institute of Gene Biology, Russian Academy of Sciences
期: 卷 484, 编号 1 (2019)
页面: 45-47
栏目: Biochemistry, Biophysics, and Molecular Biology
URL: https://journals.rcsi.science/1607-6729/article/view/212729
DOI: https://doi.org/10.1134/S1607672919010125
ID: 212729

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详细

In this paper, we demonstrate that passing-through transcription suppresses the activity of the white gene enhancer integrated into the intron. At the same time, the SV40 transcription terminators flanking the transgene can completely remove the inhibitory effect of transcription.