Отправить статью по E-mail Influence of Sodium Selenite on the mRNA Expression of the Mammalian Selenocysteine-Containing Protein Genes in Testicle and Prostate Cancer Cells
- Авторы: Kuznetsova Y.P.1, Goltyaev M.V.2, Gorbacheva O.S.3, Novoselov S.V.2, Varlamova E.G.2, Fesenko E.E.2
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Учреждения:
- Voronezh State University of Engineering Technology
- Institute of Cell Biophysics
- Institute of Theoretical and Experimental Biophysics
- Выпуск: Том 480, № 1 (2018)
- Страницы: 131-134
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212260
- DOI: https://doi.org/10.1134/S1607672918030018
- ID: 212260
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Аннотация
The sodium selenite concentration that reduces the viability of Du-145 human prostate adenocarcinoma cells and F-9 mouse testicular teratocarcinoma cells was determined. We investigated the effect of sodium selenite on the mRNA expression level of the genes encoding mammalian selenocysteine-containing glutathione peroxidases and thioredoxin reductases (key antioxidant enzymes involved in the regulation of intracellular thiol redox balance), endoplasmic reticulum selenoproteins, and selenoproteins located in the testes and prostate.
Об авторах
Yu. Kuznetsova
Voronezh State University of Engineering Technology
Email: goltayev@mail.ru
Россия, Voronezh, 394036
M. Goltyaev
Institute of Cell Biophysics
Автор, ответственный за переписку.
Email: goltayev@mail.ru
Россия, Pushchino, Moscow oblast, 142290
O. Gorbacheva
Institute of Theoretical and Experimental Biophysics
Email: goltayev@mail.ru
Россия, Pushchino, Moscow oblast, 142290
S. Novoselov
Institute of Cell Biophysics
Email: goltayev@mail.ru
Россия, Pushchino, Moscow oblast, 142290
E. Varlamova
Institute of Cell Biophysics
Email: goltayev@mail.ru
Россия, Pushchino, Moscow oblast, 142290
E. Fesenko
Institute of Cell Biophysics
Email: goltayev@mail.ru
Россия, Pushchino, Moscow oblast, 142290
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