N-acyl dopamines induce apoptosis in PC12 cell line via the GPR55 receptor activation
- Autores: Akimov M.G.1, Ashba A.M.1, Gretskaya N.M.1, Bezuglov V.V.1
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Afiliações:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Edição: Volume 474, Nº 1 (2017)
- Páginas: 155-158
- Seção: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/211886
- DOI: https://doi.org/10.1134/S1607672917030012
- ID: 211886
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Resumo
Dopamine amides of arachidonic, docosahexaenoic, and oleic acids were found to induce apoptosis in PC12 cells, which was blocked exclusively by antagonists and preincubation agonists of the receptor GPR55, belonging to the group of non-CB1/CB2 receptors.
Sobre autores
M. Akimov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Autor responsável pela correspondência
Email: akimovmike@yandex.ru
Rússia, Moscow, 117997
A. Ashba
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: akimovmike@yandex.ru
Rússia, Moscow, 117997
N. Gretskaya
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: akimovmike@yandex.ru
Rússia, Moscow, 117997
V. Bezuglov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Email: akimovmike@yandex.ru
Rússia, Moscow, 117997
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