Regeneration of jejunal wall defect using an implant based on silk fibroin fibers

I. I. Agapov; M. P. Kirpichnikov; M. M. Moisenovich; D. A. Kulikov; A. V. Goncharenko; A. Y. Arkhipova; T. V. Vasiljeva; Yu. N. Filyushkin; L. V. Arkhipova; M. S. Kotlyarova; A. V. Kulikov; A. E. Mashkov

doi:10.1134/S1607672917010045

Regeneration of jejunal wall defect using an implant based on silk fibroin fibers

Autores: Agapov I.I.¹, Kirpichnikov M.P.², Moisenovich M.M.², Kulikov D.A.³, Goncharenko A.V.², Arkhipova A.Y.², Vasiljeva T.V.², Filyushkin Y.N.³, Arkhipova L.V.⁴, Kotlyarova M.S.², Kulikov A.V.⁴, Mashkov A.E.³
Afiliações:
1. Shumakov Federal Research Center of Transplantation and Artificial Organs
2. Biological Faculty
3. Vladimirskii Moscow Regional Research Clinical Institute
4. Institute of Theoretical and Experimental Biophysics
Edição: Volume 472, Nº 1 (2017)
Páginas: 12-14
Seção: Biochemistry, Biophysics, and Molecular Biology
URL: https://journals.rcsi.science/1607-6729/article/view/211800
DOI: https://doi.org/10.1134/S1607672917010045
ID: 211800

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Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete degradation of the implant material.