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MNT Optimization for Intracellular Delivery of Antibody Fragments


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

We studied the possibility of optimizing modular nanotransporters (MNTs) for the intracellular delivery of antibody fragments into the nuclei of cells of a specified type. Basic MNT with a reduced size retaining the desired functions was obtained, and the principal possibility of obtaining an MNT carrying an antibody fragment by microbiological synthesis was shown.

Авторлар туралы

A. Ulasov

Institute of Gene Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334

Y. Khramtsov

Institute of Gene Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334

T. Lupanova

Institute of Gene Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334

A. Tsvetkova

Institute of Gene Biology; Faculty of Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334; Moscow, 119992

A. Rosenkranz

Institute of Gene Biology; Faculty of Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334; Moscow, 119992

T. Slastnikova

Institute of Gene Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334

G. Georgiev

Institute of Gene Biology

Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334

A. Sobolev

Institute of Gene Biology; Faculty of Biology

Хат алмасуға жауапты Автор.
Email: sobolev@igb.ac.ru
Ресей, Moscow, 119334; Moscow, 119992

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