Enviar artigo por via de e-mail The antitumor effect of magnetic nanodisks and DNA aptamer conjugates
- Autores: Kim P.D.1,2, Zamay S.S.1,3,4, Zamay T.N.3,5, Prokopenko V.S.6, Kolovskaya O.S.1,3, Zamay G.S.1,3, Princ V.Y.2, Seleznev V.A.2, Komonov A.I.2, Spivak E.A.1, Rudenko R.Y.5,4, Dubinina A.V.1,3,5, Komarov A.V.1,5, Denisenko V.V.1,5, Komarova M.A.1,3, Sokolov A.E.1,4, Narodov A.A.1,3, Zjivaev V.P.6, Zamay A.S.1,3,7
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Afiliações:
- Krasnoyarsk Research Center, Siberian Branch
- Institute of Semiconductor Physics, Siberian Branch
- Voino-Yasenetskii State Medical University
- Kirenskii Institute of Physics, Siberian Branch
- Siberian Federal University
- Astaf’ev Krasnoyarsk State Pedagogical University
- Institute of Chemistry and Chemical Technology, Siberian Branch
- Edição: Volume 466, Nº 1 (2016)
- Páginas: 66-69
- Seção: Biochemistry, Biophysics and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/210994
- DOI: https://doi.org/10.1134/S1607672916010154
- ID: 210994
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Resumo
Here we describe a method of forming large arrays (up to 109 pieces) of free magnetic Ni-nanodisks 50 nm thick coated on both sides with layers of 5 nm thick Au. The antitumor effect of the magnetic nickel gold-coated nanodisks and DNA aptamer conjugates was evaluated in vivo and in vitro. Under the influence of rotating magnetic field, the studied nanodisks can cause the death of Ehrlich ascites carcinoma cells.
Sobre autores
P. Kim
Krasnoyarsk Research Center, Siberian Branch; Institute of Semiconductor Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; pr. Akademika Lavrent’eva 13, Novosibirsk, 630090
S. Zamay
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University; Kirenskii Institute of Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022; Akademgorodok, Krasnoyarsk, 660036
T. Zamay
Voino-Yasenetskii State Medical University; Siberian Federal University
Autor responsável pela correspondência
Email: tzamay@yandex.ru
Rússia, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022; Svobodnyi pr. 79, Krasnoyarsk, 660041
V. Prokopenko
Astaf’ev Krasnoyarsk State Pedagogical University
Email: tzamay@yandex.ru
Rússia, ul. A. Lebedevoi 89, Krasnoyarsk, 660049
O. Kolovskaya
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022
G. Zamay
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022
V. Princ
Institute of Semiconductor Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, pr. Akademika Lavrent’eva 13, Novosibirsk, 630090
V. Seleznev
Institute of Semiconductor Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, pr. Akademika Lavrent’eva 13, Novosibirsk, 630090
A. Komonov
Institute of Semiconductor Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, pr. Akademika Lavrent’eva 13, Novosibirsk, 630090
E. Spivak
Krasnoyarsk Research Center, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036
R. Rudenko
Siberian Federal University; Kirenskii Institute of Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Svobodnyi pr. 79, Krasnoyarsk, 660041; Akademgorodok, Krasnoyarsk, 660036
A. Dubinina
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University; Siberian Federal University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022; Svobodnyi pr. 79, Krasnoyarsk, 660041
A. Komarov
Krasnoyarsk Research Center, Siberian Branch; Siberian Federal University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; Svobodnyi pr. 79, Krasnoyarsk, 660041
V. Denisenko
Krasnoyarsk Research Center, Siberian Branch; Siberian Federal University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; Svobodnyi pr. 79, Krasnoyarsk, 660041
M. Komarova
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022
A. Sokolov
Krasnoyarsk Research Center, Siberian Branch; Kirenskii Institute of Physics, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; Akademgorodok, Krasnoyarsk, 660036
A. Narodov
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022
V. Zjivaev
Astaf’ev Krasnoyarsk State Pedagogical University
Email: tzamay@yandex.ru
Rússia, ul. A. Lebedevoi 89, Krasnoyarsk, 660049
A. Zamay
Krasnoyarsk Research Center, Siberian Branch; Voino-Yasenetskii State Medical University; Institute of Chemistry and Chemical Technology, Siberian Branch
Email: tzamay@yandex.ru
Rússia, Akademgorogok, Krasnoyarsk, 660036; ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk Krai, 660022; Krasnoyarsk
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