Chronicles of A.I. Pospelov Moscow Dermatovenerology and Cosmetology Society (MDCS was founded on October 4, 1891) Bulletin of the MSDC № 1148

The 1148th meeting was held in a “face-to-face” format. In total there were 135 participants. Six people were accepted as members of the MSDVC.

A number of clinical observations were presented at the meeting. The case of severe gangrenous pyoderma with mucosal lesions is of interest due to the complexity of differential diagnosis with Wegener’s granulomatosis, while the main method confirming the diagnosis of gangrenous pyoderma is histological examination of a biopsy. The agenda also discussed the validity of the allocation of the clinical concept of “red scrotum syndrome”. Patients with red scrotum syndrome, as a rule, seek advice from a dermatologist late, which leads to a decrease in their quality of life. In the presented observation, the patient was treated as with rosacea. The clinical experience of the use of IL-17 inhibitors in the treatment of generalized pustular psoriasis of Tsumbush is also analyzed.

The scientific part of the meeting was entirely devoted to the issues of psoriasis, a disease that is a significant psychosocial problem and has a great impact on the quality of life of patients. Not only the differences between psoriasis and seborrheic dermatitis were considered, but also the similarity of the clinical picture, including the pathophysiological features of the stratum corneum, namely the generality of keratinization processes, while the leading therapeutic approach for both diseases is the use of external agents with anti-keratinizing and anti-inflammatory effects. Liposomal cream with silymarin is used for external therapy of psoriasis. Dermatocosmetic products containing silybin demonstrate a positive effect in the treatment of psoriasis, which is confirmed by the results of the study. Nevertheless, the development of effective and safe local remedies for psoriasis therapy remains an urgent problem of modern dermatology.