Problems of diagnostics of oral lichen planus

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Lichen planus is a disease most commonly found in both dermatological and dental practice. The etiology of this dermatosis is not fully understood. As a rule, with lichen planus, the organs of the gastrointestinal tract, cardiovascular, nervous, endocrine and other systems are affected. The disease can develop against the background of strong psychoemotional stress. Differential diagnosis of lichen planus is performed with leukoplakia, autoimmune pemphigus, candidiasis and lupus erythematosus.

The authors present their own clinical observation of a patient with a lichen planus of the oral mucosa, in whom a diagnostic error led to the series of unsuccessful hospitalizations, examinations, surgical interventions against the background of a gradual aggravation of the mental state.

The interest of this clinical observation is that in the case of diagnosis of lichen planus of the oral mucosa, a complete examination of the skin and all mucous membranes is necessary in order to identify the elements characteristic of this disease. Of particular importance is a biopsy with histological and immunohistochemical examination before the start of therapy. With a prolonged course of the disease, the ineffectiveness of invasive therapies requires timely administration of systemic glucocorticoids to achieve remission. Prolonged and persistent course of lichen planus of the oral mucosa can lead not only to the transformation of the process, but also to the development of psychogenic reactions.

The article shows the importance of a tandem between a dermatovenerologist, a dentist and a psychiatrist for the effective care of patients with lesions of the oral mucosa with lichen planus.

作者简介

Olga Grabovskaya

I.M. Sechenov First Moscow State Medical University

Email: olgadoctor2013@yandex.ru
ORCID iD: 0000-0002-5259-7481
SPIN 代码: 1843-1090

MD, Cand. Sci. (Med.), Professor

俄罗斯联邦, Moscow

Lyailya Kayumova

I.M. Sechenov First Moscow State Medical University

Email: avestohka2005@inbox.ru
ORCID iD: 0000-0003-0301-737X
SPIN 代码: 4391-9553

MD, Cand. Sci. (Med.), Assistant Lecturer

俄罗斯联邦, Moscow

Alena Nikulina

I.M. Sechenov First Moscow State Medical University

Email: a.niku@mail.ru
ORCID iD: 0000-0002-0736-8022
SPIN 代码: 8652-3101

MD, Graduate Student

俄罗斯联邦, Moscow

Baira Damdinova

I.M. Sechenov First Moscow State Medical University

Email: baira_d@mail.ru
ORCID iD: 0000-0002-4162-2928
SPIN 代码: 5350-3443

MD, Graduate Student

俄罗斯联邦, Moscow

Sagibat Shakhmanova

I.M. Sechenov First Moscow State Medical University

编辑信件的主要联系方式.
Email: Sonya271195@yandex.ru
ORCID iD: 0000-0001-8665-4731
俄罗斯联邦, Moscow

参考

  1. Chuikin S, Akmalova GM. Lichen planus of the oral mucosa: clinical forms and treatment. Kazan Med J. 2014;95(5):680–687. (In Russ).
  2. Alrashdan MS, Cirillo N, McCullough M. Oral lichen planus: a literature review and update. Arch Dermatol Res. 2016;308(8): 539–551. doi: 10.1007/s00403-016-1667-2
  3. Zhiltsova EE, Politov SA, Ermoshina NP, et al. Modern aspects of etiopathogenesis of lichen planus of the mucous membrane lining the oral cavity. In: Formation of public health: medical, social and clinical aspects: Collection of scientific papers. Ed. by O.E. Konovalov, S.V. Zhukov. Tver; 2020. Р. 76–81. (In Russ).
  4. Cheng YS, Gould A, Kurago Z, et al. Diagnosis of oral lichen planus: a position paper of the American Academy of Oral and Maxillofacial Pathology. Oral Sur Oral Med Oral Pathology Oral Radiology. 2016;122(3):332–354. doi: 10.1016/j.oooo.2016.05.004
  5. Clinical recommendations. Lichen is red flat. All-Russian public organization “Russian Society of Dermatovenerologists and Cosmetologists”; 2020. 34 p. (In Russ).
  6. Molochkov VA, Amkhadova MA, Molochkova YV. Lichen planus of the oral cavity as an interdisciplinary problem. Med Alphabet. 2017;4(38):52–57. (In Russ).
  7. Olisova OY, Teplyuk NP, Grabovskaya OV, Kolesova YV. Lichen planus. Russ J Skin Venereal Diseases. 2020;23(5):356–360. (In Russ). doi: 10.17816/dv59113
  8. Serazetdinova AR, Trunin DA, Kirillova VP, et al. Analysis of a clinical case of a patient with red flat lichen of the oral mucosa associated with the Epstein-Barr virus. Actual Problems Dentistry. 2020;16(1):35–41. (In Russ). doi: 10.18481/2077-7566-20-16-1-35-41
  9. Grigoriev SS, Zhovtyak PB, Letaeva OV. Oral lichen planus. Review. Ural Med J. 2014;5(119):8–15. (In Russ).
  10. Vijayan AK, Muthukrishnan A, Vidyadharan M, Nair AM. Role of human papilloma virus in malignant transformation of oral lichen planus: a systematic review. J Pharm Bioallied Sci. 2021;13(Suppl 1):S62–S67. doi: 10.4103/jpbs.JPBS_836_20
  11. Makeeva IM, Volkov AG, Dikopova NZ, Makarenko NV. The determination of electrochemical potentials in the oral cavity, as a method of diagnosing galvanic syndrome contributing to the development of diseases of the mucous membrane. Head Neck. 2018;(1):42–45. (In Russ). doi: 10.25792/HN.2018.6.1.42–45
  12. Martin MD, Broughton S, Drangsholt M. Oral lichen plantus and dental materials: a case-control study. Contact Dermatitis. 2003;48(6):331–336. doi: 10.1034/j.1600-0536.2003.00146.x
  13. Tiunova NV. Lichen planus: choice of treatment method. Review. Dentistry. 2011;1(72):14–15. (In Russ).
  14. Dorozhenok IY, Snarskaya ES, Mikhailova M. Lichen planus and itch-related psychosomatic disorders. Russ J Skin Venereal Diseases. 2021;24(6):543–551. doi: 10.17816/dv100612
  15. Hanova SA, Sirak SV, Chebotarev VV, Sirak AG. Lichen planus of the oral mucosa, modern methods of local treatment. Int J Applied Fundamental Res. 2014;(2):197–202. (In Russ).
  16. Skin and venereal diseases: textbook. Ed. by O.Yu. Olisova. Moscow: Practical Medicine; 2015. 288 p. (In Russ).
  17. Kurago ZB. Etiology and pathogenesis of oral lichen planus: an overview. Oral Sur Oral Med Oral Pathology Oral Radiology. 2016;122(1):72–80. doi: 10.1016/j.oooo.2016.03.011
  18. Chiang CP, Chang JY, Wang YP, et al. Oral lichen planus ― differential diagnoses, serum autoantibodies, hematinic deficiencies, and management. J Formosan Med Association. 2018;117(9):756–765. doi: 10.1016/j.jfma.2018.01.021
  19. Red lichen planus of the oral mucosa. Clinic, diagnosis, treatment and prevention. Methodological recommendations. Department of Health of Moscow; 2021. 27 p. (In Russ).

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2. Fig. 1. Patient L., 45 years old, diagnosis of lichen planus: on the mucous membrane of the cheeks on both sides (a, b) there are infiltrated papular rashes of white color, prone to fusion with the formation of a peculiar mesh.

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3. Fig. 2. The same patient: on the dorsal surface of the tongue there are weakly infiltrated whitish foci with clear boundaries and a whitish-pink scar about 2.5 cm long, covered with a slight fibrinous plaque, slightly painful on palpation; papillae around the scar are absent.

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4. Fig. 3. The same patient: in the area of the medial surface of the right ankle joint, there is a typical pinkish-bluish papule of a flat shape with clear boundaries, polygonal outlines, on the surface of which a Wickham grid can be found without subjective sensations.

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5. Fig. 4. The same patient, condition after treatment (a, b, c): marked regression of rashes on the oral mucosa.

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6. Fig. 5. The same patient, the condition after treatment: in the area of the right ankle joint, there is a flattening of the papule with an outcome in pigmentation.

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版权所有 © Grabovskaya O.V., Kayumova L.N., Nikulina A.S., Damdinova B., Shakhmanova S., 2022

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