Email this article New potentialities of therapy for atopic dermatitis
- Authors: Olisova O.Y.1
-
Affiliations:
- I.M. Setchenov First Moscow State Medical University
- Issue: Vol 18, No 6 (2015)
- Pages: 38-41
- Section: Articles
- URL: https://journals.rcsi.science/1560-9588/article/view/37021
- DOI: https://doi.org/10.17816/dv37021
- ID: 37021
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Abstract
Published data on the pathogenesis and main methods of therapy for atopic dermatitis (AD) are analyzed. Defects in the barrier function of the skin are regarded as one of the major phenotypical signs of AD. Therapy of AD is a difficult problem; however, the use of hydratants and oily means remains the base topical therapy to repair the barrier function of the skin. A new lipid-replenishing cream for topical therapy of AD, Xeracalm, is presented. The cream was used in 15 patients aged 15-32 years with mild AD. The efficiency was evaluated by objective criteria (erythema, desquamation, dryness) and subjective sensations (skin “shrinkage”), SCORAD index, and dermatological quality of life index. The studies demonstrated high efficiency of Xeracalm cream, which could be recommended for therapy of AD and maintenance of clinical remission.
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##article.viewOnOriginalSite##About the authors
Olga Yu. Olisova
I.M. Setchenov First Moscow State Medical University
Email: olisovaolga@mail.ru
MD, PhD, DSc, prof. 119991, Moscow, Russia
References
- Кочергин Н.Г., Румянцева Е.Е., Кондрашов Г.В., Траксель Л.В. Пимекролимус при иммунодерматозах. Русский медицинский журнал. 2003; 11(17): 953-56.
- Хаитов Р.М., Игнатьева Г.А., Сидорович И.Г. Иммунология. М.: Медицина; 2000.
- Иванов О.Л., Львов А.Н., Миченко А.В. Атопический дерматит: современные представления. Русский медицинский журнал. 2007; 15(19): 1362-6.
- Смирнова Г.И. Современные технологии диагностики и лечения тяжелых форм аллергодерматозов у детей. Москва-Тверь: Альба Плюс; 2006.
- Аравийская Е.Р., Соколовский Е.В. Сухость кожи. Причины и механизмы возникновения. Принципы коррекции. Журнал дерматовенерологии и косметологии. 2002; 2: 10-3.
- Мордовцева В.В., Масюкова С.А. Роль средств лечебной косметики в уходе за кожей при атопическом дерматите. Consilium medicum. Дерматология. 2011; 4: 4-7.
- Arikawa J., Ishibashi M., Kawashima M., Takagi Y., Ichikawa Y., Imokawa G. Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus. J. Invest. Dermatol. 2002; 119(2): 433-9.
- Akdis C., Akdis M., Bieber T., Bindslev-Jensen C., Boguniewicz M., Eigenmann P., et al.; European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology. Diagnosis and treatment of atopic dermatitis in children and adults: Europen Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J. Allergy Clin. Immunol. 2006; 118(1): 152-69.
- Короткий Н.Г., Тихомиров А.А., Гамаюнов Б.Н. Современные средства лечебно-косметического ухода и специфической гигиены в лечении атопического дерматита у детей. Клиническая дерматология и венерология. 2008; 4: 67-71.
