Email this article Matrix metalloproteinase 9 is a marker of chronic inflammation in cutaneous vasculitis
- Authors: Chernigova E.I1, Aksenenko M.B1, Ruksha T.G.1
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Affiliations:
- V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
- Issue: Vol 18, No 1 (2015)
- Pages: 34-37
- Section: Articles
- URL: https://journals.rcsi.science/1560-9588/article/view/36947
- DOI: https://doi.org/10.17816/dv36947
- ID: 36947
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Abstract
The morphohistological picture of skin biopsy specimens from patients with cutaneous vasculitis is presented. Dilatation of dermal vessels and increase of their numbers, increase of perivascular lymphocytic infiltration of the derma in comparison with the parameters in biopsy specimens of the skin from healthy volunteers indicates neoangiogenesis and pathological dilatation of the dermal capillaries. High concentrations of matrix metalloproteinase 9 (MMP-9) and its homogenous dissemination in the specimens from patients with dermal vasculitis presumably indicate the regulatory role of MMP in extracellular matrix remodeling and neoangiogenesis.
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##article.viewOnOriginalSite##About the authors
E. I Chernigova
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: katrinas_24@mail.ru
аспирант 660022, Krasnoyarsk, Russian Federation
M. B Aksenenko
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: aksenenko_mariya@mail.ru
кандидат мед. наук 660022, Krasnoyarsk, Russian Federation
Tatyana G. Ruksha
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University
Email: tatyana_ruksha@mail.ru
MD, PhD 660022, Krasnoyarsk, Russian Federation
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