Systemic processes in influenza in fection, as a triggers of the development of somatic pathology in patients at risk


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Pathogenetic mechanisms of influenza infection on the one hand are the triggering factor of certain diseases (asthma, neurological diseases and others.), on the other hand they worsen the course of concomitant somatic pathology, leading to severe, complicated course of infection and lethal outcomes in high-risk groups. The two components of the flu - a syndrome of systemic inflammation, which is manifested in the overproduction of cytokines and generalized vascular thrombosis syndrome (VTS) are the most important components of the pathogenesis of influenza and play a critical role in the development of severe infections, especially in patients with a history ofpremorbid background. Analysis of the pathogenic mechanisms of diseases, at risk, is necessary for the development of a comprehensive targeted tactics prevention, treatment and medical examination that will prevent mortality in these groups.

作者简介

E. Deeva

Research Institute of Influenza

Email: edeeva@hotmail.com
канд. мед. наук заведующая специализированной клиникой ФГБУ НИИ гриппа Минздрава России 15/17, Professora Popova str., Saint Petersburg, 197376

T. Zubkova

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

N. Dunaeva

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

S. Koltsebaeva

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

G. Chelaeva

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

E. Tumanova

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

E. Tsypkin

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

Yu. Deeva

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

Yu. Shevchik

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

O. Kiselev

Research Institute of Influenza

15/17, Professora Popova str., Saint Petersburg, 197376

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