Evaluation of the virulence of Vibrio parahaemolyticus strains isolated in Russia and contiguous states


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One hundred and ninety-six Vibrio parahaemolyticus strains that are etiological agents causing outbreaks and sporadic cases of food toxicoinfections and isolated from the environments of Russia, Ukraine, and Turkmenia are characterized by virulence-associated phenotypic and genotypic signs. Most clinical strains were found to contain the genes of the major pathogenicity factors - thermostable direct hemolysin (TDH) and/or TDH-related hemolysin (TRH); however, a large number of pathogens lack these genes. In all likelihood, these strains can cause human diseases, by producing other toxic substances. The presence of the trh gene correlated with that and expression of the urease genes. Comparative analysis of the findings has demonstrated that the results of polymerase chain reaction detection of the tdh gene do not always agree with the signs of hemolytic activity on the Wagatsum medium (Kanagawa phenomenon). Therefore, both tests that complement each other are recommended for a fuller evaluation of the potential danger of Vibrio parahaemolyticus strains.

作者简介

Oksana Shalu

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

Email: oksankashalu@yandex.ru
мл. науч. сотр; ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

E Golenishcheva

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

L Smolikova

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

G Gal'tseva

ФГУЗ Причерноморская противочумная станция, Новороссийск

ФГУЗ Причерноморская противочумная станция, Новороссийск

N Bozhko

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

E Monakhova

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

ФГУЗ Научно-исследовательский противочумный институт, Ростов-на-Дону

O Shalu

Anti-Plague Research Institute, Rostov-on-Don

Anti-Plague Research Institute, Rostov-on-Don

Ye Golenishcheva

Anti-Plague Research Institute, Rostov-on-Don

Anti-Plague Research Institute, Rostov-on-Don

L Smolikova

Anti-Plague Research Institute, Rostov-on-Don

Anti-Plague Research Institute, Rostov-on-Don

G Galtseva

Black-Sea Anti-Plague Station, Novorossiysk

Black-Sea Anti-Plague Station, Novorossiysk

N Bozhko

Anti-Plague Research Institute, Rostov-on-Don

Anti-Plague Research Institute, Rostov-on-Don

Ye Monakhova

Anti-Plague Research Institute, Rostov-on-Don

Anti-Plague Research Institute, Rostov-on-Don

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