Synthesis of new heterocyclic systems—substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]


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Methods have been developed for the synthesis of new heterocyclic systems, spiro[chromene-4,3′- indoles] and spiro[indole-3,4′-quinolines] by the base-catalyzed domino reaction of isatins with 5,5-dimethylcyclohexane- 1,3-dione (or 5,5-dimethyl-3-anilinocyclohex-2-en-1-one) and ethyl cyanoacetate.

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S. Pogosyan

Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry

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Email: karik7507@rambler.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014

Dzh. Avakimyan

Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: karik7507@rambler.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014

H. Stepanyan

Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry

Email: karik7507@rambler.ru
亚美尼亚, pr. Azatutyan 26, Yerevan, 0014

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