New Azetidinone Building Block for Carbapenems


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详细

A new versatile building block for the synthesis of carbapenems, (3S,4R)-3-{(R)-1-[tert-butyl-(dimethyl)silyloxy]ethyl}-4-[(2RS)-5-(4-methoxybenzyloxy)pent-3-yn-2-yl]azetidin-2-one, has been obtained by zinc-promoted alkylation of (3R,4R)-(+)-3-{(R)-1-[tert-butyl(dimethyl)silyloxy]ethyl}-2-oxoazetidin-4-yl acetate with 1-[(4-bromopent-2-yn-1-yloxy)methyl]-4-methoxybenzene.

作者简介

L. Khasanova

Ufa Institute of Chemistry, Ufa Federal Research Center

Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

Z. Valiullina

Ufa Institute of Chemistry, Ufa Federal Research Center

Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

A. Galeeva

Ufa Institute of Chemistry, Ufa Federal Research Center

Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

V. Egorov

Ufa Institute of Chemistry, Ufa Federal Research Center

Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

F. Gimalova

Ufa Institute of Chemistry, Ufa Federal Research Center

编辑信件的主要联系方式.
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan

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