New Azetidinone Building Block for Carbapenems
- 作者: Khasanova L.S.1, Valiullina Z.R.1, Galeeva A.M.1, Egorov V.A.1, Gimalova F.A.1
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隶属关系:
- Ufa Institute of Chemistry, Ufa Federal Research Center
- 期: 卷 55, 编号 3 (2019)
- 页面: 377-380
- 栏目: Short Communication
- URL: https://journals.rcsi.science/1070-4280/article/view/220131
- DOI: https://doi.org/10.1134/S1070428019030187
- ID: 220131
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详细
A new versatile building block for the synthesis of carbapenems, (3S,4R)-3-{(R)-1-[tert-butyl-(dimethyl)silyloxy]ethyl}-4-[(2RS)-5-(4-methoxybenzyloxy)pent-3-yn-2-yl]azetidin-2-one, has been obtained by zinc-promoted alkylation of (3R,4R)-(+)-3-{(R)-1-[tert-butyl(dimethyl)silyloxy]ethyl}-2-oxoazetidin-4-yl acetate with 1-[(4-bromopent-2-yn-1-yloxy)methyl]-4-methoxybenzene.
作者简介
L. Khasanova
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan
Z. Valiullina
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan
A. Galeeva
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan
V. Egorov
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan
F. Gimalova
Ufa Institute of Chemistry, Ufa Federal Research Center
编辑信件的主要联系方式.
Email: fangim@anrb.ru
俄罗斯联邦, pr. Oktyabrya 71, Ufa, 450054 Bashkortostan
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