Condensation Reactions of Sulfur-Containing Chalcone Analogs
- 作者: Andin A.N.1, Shvalov D.A.1
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隶属关系:
- Far Eastern Federal University
- 期: 卷 54, 编号 9 (2018)
- 页面: 1329-1332
- 栏目: Article
- URL: https://journals.rcsi.science/1070-4280/article/view/218886
- DOI: https://doi.org/10.1134/S1070428018090105
- ID: 218886
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详细
Three-component condensation of heterocyclic chalcone analogs containing a thiophene ring with 5,5-dimethylcyclohexane-1,3-dione (dimedone) and ammonia at 140–145°C under pressure afforded functionalized 1,4,5,6,7,8-hexahydroquinoline derivatives; the corresponding triketones were formed under milder conditions (100–105°C). The condensation of 1,3-di(thiophen-2-yl)prop-2-en-1-one with dimedone and ammonia under harsh conditions unexpectedly produced functional 1,2,3,4,5,6,7,8,9,10-decahydroacridine derivative. Heterocyclic chalcone analogs reacted with ethyl acetoacetate in the presence of ammonia to give cyclocondensation products, ethyl 2-oxocyclohex-3-ene-1-carboxylates.
作者简介
A. Andin
Far Eastern Federal University
编辑信件的主要联系方式.
Email: andin.an@dvfu.ru
俄罗斯联邦, Universitetskii pr. bld. L, Russkii Island, Vladivostok, 690922
D. Shvalov
Far Eastern Federal University
Email: andin.an@dvfu.ru
俄罗斯联邦, Universitetskii pr. bld. L, Russkii Island, Vladivostok, 690922
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