Preparation of magnetite nanoparticles modified with poly( о -phenylenediamine) and their use as drug carriers

I. S. Strakhov; Ya. O. Mezhuev; Yu. V. Korshak; A. L. Kovarskii; M. I. Shtil’man

doi:10.1134/S1070427216030150

Preparation of magnetite nanoparticles modified with poly(о-phenylenediamine) and their use as drug carriers

Autores: Strakhov I.S.¹, Mezhuev Y.O.¹, Korshak Y.V.¹, Kovarskii A.L.², Shtil’man M.I.¹
Afiliações:
1. Mendeleev Russian University of Chemical Technology
2. Emanuel Institute of Biochemical Physics
Edição: Volume 89, Nº 3 (2016)
Páginas: 447-450
Seção: Macromolecular Compounds and Polymeric Materials
URL: https://journals.rcsi.science/1070-4272/article/view/213678
DOI: https://doi.org/10.1134/S1070427216030150
ID: 213678

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A procedure was suggested for preparing nanoparticles consisting of magnetite and poly(o-phenylenediamine) by combining the hydrolysis of a mixture of iron(II) and (III) sulfates with oxidative polymerization of o-phenylenediamine. These nanoparticles efficiently bind phenylalanine, thyrosine, tryptophan, and doxorubicin in aqueous solution.