Mass Spectrometry Profiling of the Protein Composition of Blood Plasma of Colorectal Cancer Patients


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The objective of the study is themass spectrometry analysis of the protein composition in blood plasma samples of large intestine cancer patients. Protein profiles of 58 blood plasma samples of large intestine cancer patients and healthy volunteers are analyzed using ultrahigh-resolution panoramic mass spectrometry. It is shown that the coincidence of identifications in the protein composition samples of intestine cancer patients and healthy men is 60–80%. Samples of intestines cancer patients contain proteins involved in the interaction with ribonucleic acid, proteins, and lowmolecular substrata.

作者简介

A. Kaysheva

Institute of Biomedical Chemistry

编辑信件的主要联系方式.
Email: kaysheva1@gmail.com
俄罗斯联邦, Pogodinskaya ul. 10/8, Moscow, 119121

A. Kopylov

Institute of Biomedical Chemistry

Email: kaysheva1@gmail.com
俄罗斯联邦, Pogodinskaya ul. 10/8, Moscow, 119121

T. Pleshakova

Institute of Biomedical Chemistry

Email: kaysheva1@gmail.com
俄罗斯联邦, Pogodinskaya ul. 10/8, Moscow, 119121

N. Kushlinskii

N. N. Blokhin National Medical Research Centre of Oncology

Email: kaysheva1@gmail.com
俄罗斯联邦, Kashirskoe sh. 23, Moscow, 115478

V. Nikitaev

National Research Nuclear University “MEPhI”

Email: kaysheva1@gmail.com
俄罗斯联邦, Kashirskoe sh. 31, Moscow, 115409

E. Druzhinina

National Research Nuclear University “MEPhI”

Email: kaysheva1@gmail.com
俄罗斯联邦, Kashirskoe sh. 31, Moscow, 115409

A. Archakov

Institute of Biomedical Chemistry

Email: kaysheva1@gmail.com
俄罗斯联邦, Pogodinskaya ul. 10/8, Moscow, 119121

Yu. Ivanov

Institute of Biomedical Chemistry

Email: kaysheva1@gmail.com
俄罗斯联邦, Pogodinskaya ul. 10/8, Moscow, 119121

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