电邮这篇文章 Preparation of a carbon-14 analog of 2-[2-(4-(dibenzo[b, f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy]ethanol
- 作者: Saadatjoo N.1, Javaheri M.1,2, Saemian N.2, Amini M.3
-
隶属关系:
- Department of Organic Chemistry, Faculty of Chemistry
- Applied Radiations Research School
- Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design and Development Research Center
- 期: 卷 58, 编号 5 (2016)
- 页面: 528-531
- 栏目: Article
- URL: https://journals.rcsi.science/1066-3622/article/view/223551
- DOI: https://doi.org/10.1134/S1066362216050131
- ID: 223551
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
订阅存取
详细
2-[2-(4-(Dibenzo[b, f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy]ethanol (Quetiapine) labeled with 14C in 11-position was synthesized in five steps from [carboxy-14C]anthranilic acid. The key precursor of the target product is [11-14C]dibenzothiazepin-11(10H)-one. The reaction is performed as one-pot process.
作者简介
N. Saadatjoo
Department of Organic Chemistry, Faculty of Chemistry
编辑信件的主要联系方式.
Email: nsaadatjoo@semnan.ac.ir
伊朗伊斯兰共和国, Semnan
M. Javaheri
Department of Organic Chemistry, Faculty of Chemistry; Applied Radiations Research School
Email: nsaadatjoo@semnan.ac.ir
伊朗伊斯兰共和国, Semnan; Tehran
N. Saemian
Applied Radiations Research School
Email: nsaadatjoo@semnan.ac.ir
伊朗伊斯兰共和国, Tehran
M. Amini
Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design and Development Research Center
Email: nsaadatjoo@semnan.ac.ir
伊朗伊斯兰共和国, Tehran, 14176
