Methods of chemical and phase composition analysis of gallstones
- Авторы: Suvorova E.I.1, Pantushev V.V.1,2, Voloshin A.E.1
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Учреждения:
- Shubnikov Institute of Crystallography, Federal Center Crystallography and Photonics
- Pirogov Municipal Clinical Hospital no. 1
- Выпуск: Том 62, № 6 (2017)
- Страницы: 817-830
- Раздел: Review
- URL: https://journals.rcsi.science/1063-7745/article/view/191395
- DOI: https://doi.org/10.1134/S1063774517060232
- ID: 191395
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Аннотация
This review presents the instrumental methods used for chemical and phase composition investigation of gallstones. A great body of data has been collected in the literature on the presence of elements and their concentrations, obtained by fluorescence microscopy, X-ray fluorescence spectroscopy, neutron activation analysis, proton (particle) induced X-ray emission, atomic absorption spectroscopy, high-resolution gamma-ray spectrometry, electron paramagnetic resonance. Structural methods—powder X-ray diffraction, infrared spectroscopy, Raman spectroscopy—provide information about organic and inorganic phases in gallstones. Stone morphology was studied at the macrolevel with optical microscopy. Results obtained by analytical scanning and transmission electron microscopy with X-ray energy dispersive spectrometry are discussed. The chemical composition and structure of gallstones determine the strategy of removing stone from the body and treatment of patients: surgery or dissolution in the body. Therefore one chapter of the review describes the potential of dissolution methods. Early diagnosis and appropriate treatment of the disease depend on the development of clinical methods for in vivo investigation, which gave grounds to present the main characteristics and potential of ultrasonography (ultrasound scanning), magnetic resonance imaging, and X-ray computed tomography.
Об авторах
E. Suvorova
Shubnikov Institute of Crystallography, Federal Center Crystallography and Photonics
Автор, ответственный за переписку.
Email: suvorova@crys.ras.ru
Россия, Moscow
V. Pantushev
Shubnikov Institute of Crystallography, Federal Center Crystallography and Photonics; Pirogov Municipal Clinical Hospital no. 1
Email: suvorova@crys.ras.ru
Россия, Moscow; Moscow
A. Voloshin
Shubnikov Institute of Crystallography, Federal Center Crystallography and Photonics
Email: suvorova@crys.ras.ru
Россия, Moscow
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