PROCATHEPSIN B AND ENDOGENOUS INHIBITORS OF CYSTEINE PROTEASES IN TUMORS OF REPRODUCTIVE SYSTEM
- Authors: Gashenko E.A.1, Lebedeva V.A2, Russkikh G.S3, Tsykalenko E.A2, Pupyshev A.B1, Brak I.V1, Korolenko T.A1
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Affiliations:
- Scientific Research Institute of Physiology & Basic Medicine
- Novosibirsk State Medical University
- Scientific Research Institute of Biochemistry
- Issue: Vol 22, No 5 (2017)
- Pages: 261-265
- Section: Articles
- URL: https://journals.rcsi.science/1028-9984/article/view/40376
- DOI: https://doi.org/10.18821/1028-9984-2017-22-5-261-265
- ID: 40376
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##article.viewOnOriginalSite##About the authors
Elena A. Gashenko
Scientific Research Institute of Physiology & Basic Medicine
Email: elena.gashenko@gmail.com
MD, Researcher of the Laboratory of Experimental Models of Neuron Degenerative Processes. Novosibirsk, 630117, Russian Federation Novosibirsk, 630117, Russian Federation
V. A Lebedeva
Novosibirsk State Medical UniversityNovosibirsk, 630091, Russian Federation
G. S Russkikh
Scientific Research Institute of BiochemistryNovosibirsk, 630117, Russian Federation
E. A Tsykalenko
Novosibirsk State Medical UniversityNovosibirsk, 630091, Russian Federation
A. B Pupyshev
Scientific Research Institute of Physiology & Basic MedicineNovosibirsk, 630117, Russian Federation
I. V Brak
Scientific Research Institute of Physiology & Basic MedicineNovosibirsk, 630117, Russian Federation
T. A Korolenko
Scientific Research Institute of Physiology & Basic MedicineNovosibirsk, 630117, Russian Federation
References
- Каприн А.Д., Старинский В.В., Петрова Г.В., ред. Злокачественные новообразования в России в 2015 году (заболеваемость и смертность). М.: МНИОИ им. П.А. Герцена - филиал ФГБУ «НМИРЦ» Минздрава России; 2017.
- Joyce J.A., Baruch A., Chehade K., Meyer-Morse N., Giraudo E., Tsai F.Y. et al. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell. 2004; 5(5): 443-53.
- Elliott E., Sloane B.F. The procathepsin B in cancer. Perspect. Drug Des. 1996; (6): 12-32.
- Tan G.J., Peng Z.K., Lu J.P., Tang F.Q. Cathepsins mediate tumor metastasis. World J. Biol. Chem. 2013; 26; 4(4): 91-101.
- Turk V., Stoka V., Vasiljeva O., Renko M., Sun T., Turk B., Turk D. Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim. Biophys. Acta. 2012; 1824(1): 68-88.
- Короленко Т.А. Цистатины - биологическая роль и нарушения в патологии. Вестник Российской АМН. 2008; (4): 43-7.
- Turk V., Stoka V., Turk D. Cystatins: biochemical and structural properties, and medical relevance. Front. Biosci. 2008, 13, 5406-20.
- Levičar N., Kos J., Blejec A., Golouh R., Vrhovec I., Frkovič-Grazio S., Lah T. Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Det. Prev. 2002; 26: 42-9.
- Спирина Л.В., Кондакова И.В. Роль специфического внутриклеточного протеолиза в онкогенезе. Вопр. онкол. 2008; 54(6): 690-4.
- Korolenko T.A., Kisarova Y.A, Filjushina E.E., Machova E. In: Macrophages: Life Cycle, Functions and Diseases (Takahashi R., Kai H. Eds.). New York: Nova Science Publishers; 2012: 249-76.
- Гашенко Е.А., Лебедева В.А., Короленко Т.А., Гаврилова Н.И., Филатова Т.Г., Цикаленко Е.А. и др. Концентрация прокатепсина В и ингибитора цистеиновых протеаз в биологических жидкостях при развитии опухолей. Бюллетень СО РАМН. 2010; 30(4):110-5.
- Kos J., Krasovec M., Cimerman N., Nielsen H.J., Christensen I.J., Brünner N. Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis. Clin. Cancer Res. 2000; 6(2): 505-11.
- Wegiel B., Jiborn T., Abrahamson M., Helczynski L., Otterbein L., Persson J.L., Bjartell A. Cystatin C is downregulated in prostate cancer and modulates invasion of prostate cancer cell via MAPK/Erk and androgen receptor pathways. PLoS One. 2009; 4(11): e7953.
- Gashenko E.A., Lebedeva V.A., Brak I.V., Tsykalenko E.A., Vinokurova G.V., Korolenko T.A. Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancer». Int. J. Circumpolar Health. 2013, 72: 21215.
- Kolwijck E., Kos J., Obermajer N., Span P.N., Thomas C.M., Massuger L.F. et al. The balance between extracellular cathepsins and cystatin C is of importance for ovarian cancer. Eur. J. Clin. Invest. 2010; 40: 591-9.
- Lah T.T., Kokalj-Kunovar M., Kastelic L., Babnik J., Stolfa A., Rainer S. et al. Cystatins and stefins in ascites fluid from ovarian carcinoma. Cancer Lett. 1992; 61: 243-53.
- Nishikawa H., Ozaki Y., Nakanishi T., Blomgren K., Tada T., Arakawa A. et al. The role of cathepsin B and cystatin C in the mechanisms of invasion by ovarian cancer. Gynecol. Oncol. 2004; 92(3): 881-6.
- Takaya A., Peng W.-X., Ishino K., Kudo M., Yamamoto T., Wada R. et al. Cystatin B as a potential diagnostic biomarker in ovarian clear cell carcinoma. Int. J. Oncol. 2015; 46(4): 1573-81. doi: 10.3892/ijo.2015.2858
- Kolwijck E., Massuger L.F., Thomas C.M., Span P.N., Krasovec M., Kos J. et al. Cathepsins B, L and cystatin C in cyst fluid of ovarian tumors. J. Cancer Res. Clin. Oncol. 2010; 136: 771-8.
- Mussap M., Plebani M. Biochemistry and clinical role of human cystatin C. Crit. Rev. Clin. Lab. Sci. 2004; 41(5-6): 467-550.
- Kos J., Lah T.T. Cysteine proteases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer (review). Oncol. Rep. 1998; 5(6): 1349-61.
- Berdowska I. Cysteine proteases as disease markers. Clin. Chim. Acta. 2004; 342(1-2): 41-69.