EVALUATION OF SINGLE NUCLEOTIDE POLYMORPHISMS -819C/T, -592C/A IL-10 IN PATIENTS WITH RHEUMATOID ARTHRITIS AS A GENETIC RISK FACTOR
- 作者: Stashkevich D.1, Suslova T.1,2, Burmistrova A.1
-
隶属关系:
- Chelyabinsk State University
- Chelyabinsk Regional Blood Transfusion Station
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 572-574
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120305
- DOI: https://doi.org/10.31857/S102872210006978-0
- ID: 120305
如何引用文章
全文:
详细
The frequency distribution of the occurrence of alleles, genotypes and combinations of genotypes formed by SNPs -819, -592 IL-10 was assessed in this research. It was established that in the group of patients with RA, the distribution corresponds to that in European populations. No association of genetic polymorphism of SNPs -819, -592 IL-10 with a predisposition to RA in the Russians of the Chelyabinsk region was found.
作者简介
D. Stashkevich
Chelyabinsk State University
编辑信件的主要联系方式.
Email: stashkevich_dary@mail.ru
cand. biol. Sci., Associate Professor, Department of Microbiology, Immunology and General Biology, Biological Faculty,
Chelyabinsk
俄罗斯联邦T. Suslova
Chelyabinsk State University;Chelyabinsk Regional Blood Transfusion Station
Email: fake@neicon.ru
cand. med. Sci., Associate Professor of the Department of Microbiology, Immunology and General Biology, Biological Faculty;
head. OMBD,
Chelyabinsk
俄罗斯联邦A. Burmistrova
Chelyabinsk State University
Email: fake@neicon.ru
dr. med. Sci., Head of the Department of Microbiology, Immunology and General Biology, Faculty of Biology,
Chelyabinsk
俄罗斯联邦参考
- Сташкевич Д. С. Аллели и генотипы генов основных цитокинов и их межгенные и внутригенные связи в ассоциации с ревматоидным артритом у русской и башкирской популяций. Автореферат диссертации на соискание ученой степени кандидата биологических наук. Челябинск, 2009, 23c.
- Zhang T.-P., Lv, T.-T., Xu, S.-Z., Pan, H.-F., & Ye, D.-Q. Association of interleukin-10gene single nucleotide polymorphisms with rheumatoid arthritis in a Chinese population. Postgraduate Medical Journal, 2018, 94(1111), pp. 284–288.
- Liu Q., Yang J., He1 H., Yu Y., Lyu J. Associations between interleukin-10 polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis and metaregression. Clinical Rheumatology, 2018, available at: https://doi.org/10.1007/s10067-018-4329-2
- Аклеев А. А., Блинова Е. А., Котикова А. И. Особенности цитокинового профиля и связи полиморфизмов генов иммунной системы с уровнями сывороточных цитокинов у лиц, подвергшихся хроническому радиационному воздействию. Российский иммунологический журнал, 2018, Т. 12 (21), № 3 С. 199–204.
- Lagha A., Zidi S., Stayoussef M., Gazouani E., Kochkar R., Kochbati S., Almawi W.Y., Yacoubi-Loueslati B. Interleukin-1β, Interleukin1-Ra, Interleukin-10, and tumor necrosis factor-α polymorphisms in Tunisian patients with rheumatoid arthritis. Pathol Biol, 2015,63(4–5), pp.179–84.
