FEATURES OF FOOD HYPERSENSITIVITY IN CHILDREN WITH AUTISM SPECTRUM DISORDER
- 作者: Skirnevskaia A.1, Cherevko N.1, Khudiakova M.1, Kondakov S.2
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隶属关系:
- Siberian State Medical University
- Lomonosov Moscow State University
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 536-538
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/120294
- DOI: https://doi.org/10.31857/S102872210006965-6
- ID: 120294
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详细
According to world statistics, the incidence of autism spectrum disorders (68–100 cases per 1000 births) continues to increase in the children’s population, with boys predominating over girls (6–8: 1) [4]. Despite numerous studies on this problem, the pathogenesis of autism remains controversial. The purpose of this work is to study the clinical and immunological interactions of IgG mediated food hypersensitivity, cytokine balance and psychological parameters in children with autism spectrum disorders living in Tomsk. As a result, it was noted that children with autism are statistically significantly more often hypersensitive to cereals and dairy. Revealed changes in the concentration of a number of interleukins in the serum. A direct correlation was found between the concentration of IgG to antigens of the fungi of the genus Candida, food AG of dairy and grain and the concentration of IFNγ in serum.
作者简介
A. Skirnevskaia
Siberian State Medical University
编辑信件的主要联系方式.
Email: skirnevskaya.a@gmail.com
Tomsk
俄罗斯联邦N. Cherevko
Siberian State Medical University
Email: fake@neicon.ru
Doctor of Medical Sciences, Associate Professor of the Department of Allergology and Immunology,
Tomsk
俄罗斯联邦M. Khudiakova
Siberian State Medical University
Email: fake@neicon.ru
Tomsk 俄罗斯联邦
S. Kondakov
Lomonosov Moscow State University
Email: fake@neicon.ru
Doctor of Chemical Sciences, Doctor of Biological Sciences, Professor,
Moscow
俄罗斯联邦参考
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- Brown A. J., Brown G. D., Netea M. G., Gow N. A. Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels. Trends Microbiol. 2014;22(11):614–22.
- Vojdani A., Campbell A.W., Anyanwu E., Kashanian A., Bock K., Vojdani E. Antibodies to neuron-specific antigens in children with autism: possible cross-reaction with encephalitogenic proteins form milk, Chlamydia pneumoniae and Streptococcus group A. J Neuroimmunol. 2002;129(1–2):168–177.
