MODEL OF INFLUENCE HYPOSCIAS ON THE CELLULAR COMPONENT AND SYNTHESIS COMPONENTS EXTRACELLULAR MATRIX IN CULTURE FIBROBLASTS

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It is established, that cultivation fibroblasts in conditions hypoxia leads to decrease in their morphological heterogeneity, increase proliferative to activity and viability of cells. Causes oppression of synthesis of components extracellular matrix (collagen and elastin) and decrease expression a receptor hyaluronic acids (CD44). Duration hypoxia causes a degree of decrease.

作者简介

U. Suhovej

«Tyumen filial of the Institute Clinical Immunology»

编辑信件的主要联系方式.
Email: fake@neicon.ru

MD (Medicine), Professor, Director,

Tyumen

俄罗斯联邦

E. Kostolomova

«Tyumen filial of the Institute Clinical Immunology»;
FSBEI of Higher Education «Tyumen state medical university» of the Ministry
of Healthcare of Russian Federation

Email: lenakost@mail.ru

PhD (Biology), the assistant to faculty of pathological physiology,

Tyumen

俄罗斯联邦

I. Unger

«Tyumen filial of the Institute Clinical Immunology»

Email: fake@neicon.ru

PhD (Medicine), leading research associate,

Tyumen

俄罗斯联邦

T. Akuneeva

«Tyumen filial of the Institute Clinical Immunology»

Email: fake@neicon.ru

senior research associate,

Tyumen

俄罗斯联邦

I. Aptekar’

ANO «Tyumen institute of manual medicine»

Email: fake@neicon.ru

PhD (Medicine), Director,

Tyumen

俄罗斯联邦

参考

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  2. Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., Deans R., Keating A., Prockop D. J., Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006; 8(4):315–7
  3. Кудрявцев И. В., Хайдуков С. В., Зурочка А. В., Черешнев В. А. Применение метода проточной цитофлуориметрии для оценки пролиферативной активности клеток в медико-биологических исследованиях. Российский иммунологический журнал, 2012; 6(14), № 3–1:21–40.

版权所有 © Suhovej U.G., Kostolomova E.G., Unger I.G., Akuneeva T.V., Aptekar’ I.A., 2019

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