FLOW CYTOMETRIC ANALYSIS EXPRESSION MARKERS OF ACTIVATION ON CD4 T-LYMPHOCYTES AT RHEUMATOID ARTHRITIS
- 作者: Kostolomova E.1,2, Suhovej U.1, Unger I.1, Akuneeva T.1, Krivonosova O.2, Zenkova T.2, Makeeva O.2, Shvets O.2
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隶属关系:
- «Tyumen filial of the Institute Clinical Immunology»
- FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
- 期: 卷 22, 编号 2-1 (2019)
- 页面: 332-334
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119905
- DOI: https://doi.org/10.31857/S102872210006618-4
- ID: 119905
如何引用文章
全文:
详细
In research, it is studied coexpression CD69 and HLA-DR on sinovial T-lymphocytes at rheumatoid arthritis. The received results allow to assume, that in sinovial fluid there is a constant activation of T-cell that leads expression a marker CD69 on a surface chronically it stimulates lymphocytes only at the location the inflammation.
作者简介
E. Kostolomova
«Tyumen filial of the Institute Clinical Immunology»;FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
编辑信件的主要联系方式.
Email: lenakost@mail.ru
PhD (Biology), the assistant to faculty of pathological physiology,
Tyumen
俄罗斯联邦U. Suhovej
«Tyumen filial of the Institute Clinical Immunology»
Email: fake@neicon.ru
MD (Medicine), Professor, Director,
Tyumen
俄罗斯联邦I. Unger
«Tyumen filial of the Institute Clinical Immunology»
Email: fake@neicon.ru
PhD (Medicine), leading research associate,
Tyumen
俄罗斯联邦T. Akuneeva
«Tyumen filial of the Institute Clinical Immunology»
Email: fake@neicon.ru
senior research associate,
Tyumen
俄罗斯联邦O. Krivonosova
FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
Email: fake@neicon.ru
student,
Tyumen
俄罗斯联邦T. Zenkova
FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
Email: fake@neicon.ru
student,
Tyumen
俄罗斯联邦O. Makeeva
FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
Email: fake@neicon.ru
student,
Tyumen
俄罗斯联邦O. Shvets
FSBEI of Higher Education «Tyumen state medical university» of the Ministry of Healthcare of Russian Federation
Email: fake@neicon.ru
student,
Tyumen
俄罗斯联邦参考
- Veale D. J. Cellular and molecular perspectives in rheumatoid arthritis / D. J. Veale, C. Orr, U. Fearon // Semin Immunopathol. – 2017. doi: 10.1007/s00281-017-0633-1.
- Moore T. L. Immune Complexes in Juvenile Idiopathic Arthritis / T. L. Moore // Front Immunol. – 2016. – Vol.7. – P. 177. doi: 10.3389/fimmu.2016.00177.
- Shipkova M., Wieland E. Surface markers of lymphocyte activation and markers of cell proliferation. Clin.Chim. Acta., 2012, vol. 413, no. 17–18, pp. 1338–1349.
- Wieland E., Shipkova M. Lymphocyte surface molecules as immune activation biomarkers // Clin Biochem. – 2016. – Vol.49(4–5). – P. 347–354.
- Чередеев Н. А., Горлина Н. К., Козлов И. Г. CDмар ке ры в практике клинико-диагностических лабораторий // Клиническая лабораторная диагностика. – 1999, № 6. С. 24–31.
- Yamada H., Nakashima Y., Okazaki K., Mawatari T., Fukushi J., Oyamada A., Fujimura K., Iwamoto Y., Yoshikai Y. Preferential Accumulation of Activated Th1 Cells Not Only in Rheumatoid Arthritis But Also in Osteoarthritis Joints // The Journal of Rheumatology. – 2011. – Vol. 38, № 8. – P. 1569–1575.
- Testi R., Pulcinelli F. M., Cifone M. G., Trotta R., Torelli G., Demaria R., Frati L., Santoni A. Signaling in T lymphocytes: a possible accessory pathway initiated at the CD69 receptor. J. Immunol. Res. 1992, 4, 111–117.
