ALLERGIC DISEASES AND HELICOBACTER PYLORI INFECTION PART 1. sIgE HUMORAL IMMUNE RESPONSE TO H. PYLORI
- 作者: Gervazieva V.1, Mazurina S.1, Ilintseva N.1
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隶属关系:
- I. Mechnikov Research Institute of Vaccines & Sera
- 期: 卷 20, 编号 2 (2017)
- 页面: 275-277
- 栏目: Articles
- URL: https://journals.rcsi.science/1028-7221/article/view/119862
- ID: 119862
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详细
Serum samples, taken from 12-17 aged children with allergic and concomitant gastrointestinal diseases have been analyzed by ELISA for the total IgE, IL-4, IL-10, IgG, IgA and sIgE to H.pylori. IgE-response to H.pylori prevailed over IgA и IgG Abs and was enhanced in groups of children with allergic diseases and chronic gastroduodenitis, particularly during the exacerbation of allergy. Among children with erosive and ulcerous gastritis and also in group of non-allergic patients with chronic gastroduodenitis, the levels and frequency of sIgE to H.pylori were significantly lower than in healthy controls. The secretion of sIgE to H.pylori is supposed as one of the protective mechanisms under the conditions of chronic mucosal inflammation, associated with favorable outcomes of gastrointestinal diseases.
作者简介
V. Gervazieva
I. Mechnikov Research Institute of Vaccines & Sera
编辑信件的主要联系方式.
Email: noemail@neicon.ru
俄罗斯联邦
S. Mazurina
I. Mechnikov Research Institute of Vaccines & Sera
Email: noemail@neicon.ru
俄罗斯联邦
N. Ilintseva
I. Mechnikov Research Institute of Vaccines & Sera
Email: noemail@neicon.ru
俄罗斯联邦
参考
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