THE ROLE OF THREE-DIMENSIONAL MATRICES IMITATING BONE TISSUE REGENERATION IN THE FORMATION OF HEMATOPOIETIC STEM CELLS POOL UNDER IN VITRO CULTIVATION CONDITIONS


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详细

The study is devoted to the search criteria for creating new bioresorbable materials that form hematopoietic stem cell niches that provide vascularization of regenerating bone tissue. In the experiment, it was revealed that the formation of hematopoietic stem cells pool under in vitro cultivation conditions depends on the surface roughness index of the artificial matrix.

作者简介

L. Litvinova

Immanuel Kant Baltic Federal University

编辑信件的主要联系方式.
Email: fake@neicon.ru

Doctor of Medical Science, Head of the Basic Laboratory of Immunology and Cell Biotechnologies,

Kaliningrad

俄罗斯联邦

K. Yurova

Immanuel Kant Baltic Federal University

Email: kristina_kofanova@mail.ru

Ph.D., Researcher at the Base Laboratory of Immunology and Cell Biotechnology,

Kaliningrad

俄罗斯联邦

V. Shupletsova

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Ph.D., Researcher at the Base Laboratory of Immunology and Cell Biotechnology,

Kaliningrad

俄罗斯联邦

O. Khaziakhmatova

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Ph.D., Researcher at the Base Laboratory of Immunology and Cell Biotechnology,

Kaliningrad

俄罗斯联邦

E. Melashchenko

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Biologist of the Center for Medical Biotechnology,

Kaliningrad

俄罗斯联邦

V. Malashchenko

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Researcher, Center for Medical Biotechnologies,

Kaliningrad

俄罗斯联邦

E. Shunkin

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Engineer Researcher Basic Laboratory of Immunology and Cell Biotechnology,

Kaliningrad

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Y. Sharkeev

Institute of Strength Physics and Materials Science SB RAS

Email: fake@neicon.ru

Doctor of Physics and Mathematics, Professor, Head of Laboratory of Physics of nanostructured biocomposites,

Tomsk

俄罗斯联邦

E. Komarova

Institute of Strength Physics and Materials Science SB RAS

Email: fake@neicon.ru

Ph.D., Junior Researcher, Laboratory of Physics of Nanostructured Biocomposites,

Tomsk

俄罗斯联邦

M. Sedelnikova

Institute of Strength Physics and Materials Science SB RAS

Email: fake@neicon.ru

Doctor of Technical Science, Doctor of Technical Sciences Senior Researcher, Laboratory of Physics of Nanostructured Biocomposites,

Tomsk

俄罗斯联邦

I. Norkin

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Ph.D., student,

Kaliningrad

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K. Prokin

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

student,

Kaliningrad

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P. Ivanov

Immanuel Kant Baltic Federal University

Email: fake@neicon.ru

Researcher at the Base Laboratory of Immunology and Cell Biotechnology,

Kaliningrad

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I. Khlusov

Siberian State Medical University

Email: fake@neicon.ru

Ph.D., Professor of the Department of Morphology and General Pathology,

Tomsk

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参考

  1. Dellatore S. M., Garcia A. S., Miller W. M. Mimicking stem cell niches to increase stem cell expansion //Current opinion in biotechnology, 2008, 19 (5), P. 534–540.

版权所有 © Litvinova L.S., Yurova K.A., Shupletsova V.V., Khaziakhmatova O.G., Melashchenko E.S., Malashchenko V.V., Shunkin E.O., Sharkeev Y.P., Komarova E.G., Sedelnikova M.B., Norkin I.K., Prokin K.I., Ivanov P.A., Khlusov I.A., 2019

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