CHARACTERISTIC OF IMMUNOLOGIICAL STATUS AT PATIENTS WITH DIABETES MELLITUS TYPE2 COMBINED WITH ATHEROSCLEROTIC ARTERIAL DISEASE OF LOWER LIMBS

This article shows results of immunological status’ research at patients with diabetes mellitus type 2 (DM2) combined with atherosclerotic artery disease of lower limbs. Depending on presence of coronary artery disease (CAD) two groups of patients were formed up. With the view to validation of immunological changes’ qualities, we detected levels of IgA, IgG and IgM, circulating immune complex and blood serum cytokine’s levels. It’s elucidated, that patients with DM2 without CAD, compared with patients with CAD, have significant high levels of Interleukin 8. There were no high level markers of chronic infl ammation (IgA, IgG, circulating immune complex and pro-infl ammatory cytokines Il-1β and Il-6) detected in groups of interest.

diabetes mellitus 2 type, coronary artery disease, atherosclerotic artery disease of lower limbs, immunological status, cytokines