INFLUENCE OF THE BLOCKADE OF OPIOID RECEPTORS ON HUMORAL IMMUNITY IN MALE AND FEMALE MICE UNDER IMMOBILIZATION STRESS

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It has been established that, both in females and in males, 6 h of immobilization resulted in a pronounced suppression of the amount of PFC in the spleen. Preliminary blockade of opiate receptors led to the abolition of the effect of stress in both males and females. However, in males, the administration of one naloxone had no effect on the number of PFC, while in females, naloxone inhibited the formation of PFC by both relative and absolute indices.

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S. Gein

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences; Perm State University

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I. Sharavieva

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences

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S. Tendrykova

Institute of Ecology and Genetics of Microorganisms, Ural Branch of the Russian Academy of Sciences; Perm State University

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参考

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版权所有 © Gein S.V., Sharavieva I.A., Tendrykova S.P., 2017

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