IMMUNE DISORDERS AND ARTERIAL PRESSURE PATIENTS WITH ARTERIAL HYPERTENSION

E. V. Gavrilyuk; Гаврилюк Е. В.; A. I. Konoplya; Конопля А. И.; V. P. Mikhin; Михин В. П.; Y. V. Prokofieva; Прокофьева Ю. В.; L. N. Serikova; Серикова Л. Н.

doi:10.31857/S102872210006719-5

IMMUNE DISORDERS AND ARTERIAL PRESSURE PATIENTS WITH ARTERIAL HYPERTENSION

作者: Gavrilyuk E.¹, Konoplya A.¹, Mikhin V.¹, Prokofieva Y.¹, Serikova L.¹
隶属关系:
1. Kursk State Medical University
期: 卷 22, 编号 2-2 (2019)
页面: 736-738
栏目: ORIGINAL ARTICLES
URL: https://journals.rcsi.science/1028-7221/article/view/119457
DOI: https://doi.org/10.31857/S102872210006719-5
ID: 119457

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The study included 68 patients with arterial hypertension 1, 2 and 3 degrees, in whom the concentration of cytokines and components of the complement system was determined in the blood plasma before and after 4 weeks of systemic antihypertensive therapy. In patients with arterial hypertension prior to the onset of systemic antihypertensive therapy, changes in the level of pro-inflammatory and antiinflammatory cytokines and activation of the complement system were found in proportion to the level of blood pressure. In patients with arterial hypertension who have reached the target values of blood pressure against the background of ongoing pharmacotherapy, the severity of immune changes is significantly lower than in patients whose blood pressure has not reached the target level.