THE FUNCTIONAL ACTIVITY OF NEUTROPHILS IN PATIENTS WITH ATHEROSCLEROTIC STENOSIS OF THE CELIAC TRUNK
- 作者: Kuznetsova A.1, Dolgushina A.1, Savochkina A.1, Sumerkinа V.1, Nikushkina K.1, Emelyanovа N.2, Khaidukova I.2
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隶属关系:
- South Ural State Medical University
- Chelyabinsk Regional Hospital
- 期: 卷 20, 编号 1 (2017)
- 页面: 35-41
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119368
- ID: 119368
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The estimation of functional activity parameters of neutrophils in patients with atherosclerotic stenosis of the celiac trunk. Revealed an increase phagocytosis and lysosomal activity of peripheral blood neutrophils in this group of patients. We have identified the relationship between indicators of phagocytosis and blood flow biomechanical parameter – endothelial shear rate.
作者简介
A. Kuznetsova
South Ural State Medical University
编辑信件的主要联系方式.
Email: kuzja321@mail.ru
Assistant of the Department of Hospital Therapy
454048 Chelyabinsk, ul. Shaumyana, 118–22
俄罗斯联邦A. Dolgushina
South Ural State Medical University
Email: fake@neicon.ru
Doctor of Medical Sciences, Head of the Department of Hospital Therapy, Assistant professor
Chelyabinsk 俄罗斯联邦A. Savochkina
South Ural State Medical University
Email: fake@neicon.ru
Doctor of Medical Sciences, Professor of the Department of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics, Assistant professor
Chelyabinsk 俄罗斯联邦V. Sumerkinа
South Ural State Medical University
Email: fake@neicon.ru
PhD, Senior researcher of the Central Research Laboratory
Chelyabinsk
俄罗斯联邦K. Nikushkina
South Ural State Medical University
Email: fake@neicon.ru
PhD, Leading Researcher of the Central Research Laboratory
Chelyabinsk
俄罗斯联邦N. Emelyanovа
Chelyabinsk Regional Hospital
Email: fake@neicon.ru
PhD, Head of the Department of Ultrasound Diagnostics
Chelyabinsk
俄罗斯联邦I. Khaidukova
Chelyabinsk Regional Hospital
Email: fake@neicon.ru
Doctor Ultrasound Diagnostics
Chelyabinsk
俄罗斯联邦参考
- Göran K., Hansson M. D. Inflammation, Atherosclerosis, and Coronary Artery Disease. N. Engl. J. Med. 2005, 352, 1685–1695.
- Ross R. Atherosclerosis – an inflammatory disease. N. Engl. J. Med. 1999, 340, 115–126.
- Hosokawa T., Kumon Y., Kobayashi T., Enzan H., Nishioka Y., Yuri K., Wakiguchi H., Sugiura T. Neutrophil infiltration and oxidant-production in human atherosclerotic carotid plaques. Histol Histopathol. 2011, 26, 1, 1–11.
- Soehnlein O., Drechsler M., Döring Y., Lievens D., Hartwig H., Kemmerich K., Ortega-Gómez A., Mandl M., Vijayan S., Delia Projahn, Garlichs Ch.D., Koenen R. R., Hristov M., Lutgens E., Zernecke A., Weber Ch. Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Mol. Med. 2013, 5, 3, 471–481.
- Долгушина А. И. Иммунный статус пациентов пожилого и старческого возраста с хронической ишемией органов пищеварения. Цитокины и воспаление 2011, 10, 1, 56–59.
- Долгушин И.И., Бухарин О. В. Нейтрофилы и гомеостаз. Екатеринбург: УрОРАН, 2001, 288.
- Долгушина А. И. Функциональная активность нейтрофилов, оксид азота и перекисное окисление липидов у больных с атеросклерозом в бассейне брюшной аорты. Российский иммунологический журнал 2011, 5(14), 2, 170–176.
- Döring Y., Drechsler M., Soehnlein O., Weber Ch. Neutrophils in Atherosclerosis From Mice to Man. Arterioscler. Thromb. Vasc. Biol. 2015, 35, 288–295.
- Hellings W.E., Peeters W., Moll F. L., Piers S. R., van Setten J., Van der Spek P. J., de Vries J. P., Seldenrijk K. A., De Bruin P. C., Vink A., Velema E., de Kleijn D. P., Pasterkamp G. Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Circulation 2010, 121, 1941–1950.
- Cunningham K.S., Gotlieb A. I. The role of shear stress in the pathogenesis of atherosclerosis. Lab. Invest. 2000, 85, 1, 9–23.
- Mitchell M.J., Lin K. S., King M. R. Fluid Shear Stress Increases Neutrophil Activation via Platelet-Activating Factor. Biophys. J. 2014, 20, 106(10), 2243–2253.
- Гастроэнтерология. Клинические рекомендации. Под ред. Ивашкина В. Т. ГЭОТАР - Медиа; 2008.
- Moneta G.L., Yeager R. A., Dalman R., Antonovic R., Hall L. D., Porter J. M. Duplex ultrasound criteria for diagnosis of splanchnic artery stenosis or occlusion. J. Vasc. Surg. 1991, 14, 4, 511–518.
- Parker B.A., Trehearn T. L., Meendering J. R. Pick your Poiseuille: normalizing the shear stimulus in studies of flow-mediated dilation. J. Appl. Physiol. 2009, 107, 1357–1359.
- Генкель В.В., Салашенко А. О., Алексеева О. А., Денисенко М. Н., Шапошник И. И. Показатели эндотелиальной скорости сдвига у больных с атеросклеротическим поражением артерий каротидного бассейна. Атеросклероз и дислипидемии 2016, 2, 2(23), 58–64.
- Салашенко А. О., Генкель В. В., Сумеркина В. А., Алексеева О. А., Денисенко М. Н., Калугина С. А. Механочувствительность сосудистой стенки как дополнительный фактор оценки функции эндотелия. Здоровье семьи – 21 век, 2015, 2, 89–100.
- Хайдуков С.В., Зурочка А. В., Тотолян А. А., Черешнев В. А. Иммунофенотипирование клеток периферической крови при помощи проточной цитометрии. Стандартизация метода. Медицинская иммунология 2009, 11, 2–3, 227– 238.
- Hansson G.K., Libby P., Schönbeck U., Yan Zh.-Q. Innate and Adaptive Immunity in the Pathogenesis of Atherosclerosis. Circulation Research 2002, 23, 281–291.
- Laberge М.A., Moore K. J., Freeman M. W. Atherosclerosis and innate immune signaling. Atherosclerosis and innate immune signaling. Annals of Medicine 2005, 37, 130–140.
- Christ A., Bekkering S., Latz E., Riksend N. P. Longterm activation of the innate immune system in atherosclerosis. Seminars in Immunology 2016, 28, 384–393.
- Kiechl S., Egger G., Mayr M., Wiedermann C. J., Bonora E., Oberhollenzer F., Muggeo M., Xu Q., Wick G., Poewe W., Willeit J. Chronic infections and the risk of carotid atherosclerosis: prospective results from a large population study. Circulation 2001, 103, 1064–1070.
- Карагодин В.П., Бобрышев Ю. В., Орехов А. Н. Воспаление, иммунокомпетентные клетки, цитокины – роль в атерогенезе. Патогенез 2014, 12, 21–35
- Hansson G.K., Libby P. The immune response in atherosclerosis: A double-edged sword. Nat. Rev. Immunol. 2006, 6, 508–519.
- Akenhead M.L., Zhang X., Shin H. Y. Characterization of the shear stress regulation of CD18 surface expression by HL60-derived neutrophil-like cells. Biomech. Model Mechanobiol. 2014, 13, 4, 861–870.
- Fukuda S., Yasu T., Schmid-Schonbein G. W. Mechanisms for regulation of fluid shear stress response in circulating leukocytes. Circ. Res. 2000, 7, 86, 1, 13–18.
