NEW STRAIN OF MUTANT MICE CHARACTERIZED BY SELECTIVE RESISTANCE TO ONE OF TWO SEPTIC SHOCK PROTOCOLS
- 作者: Astrakhantseva I.1,2, Gladkova L.2, Vasilenko E.2, Tarabykin V.2,3, Drutskaya M.4, Nedospasov S.1,4,5
-
隶属关系:
- Scientific and Technological University “Sirius”
- N. Lobachevsky State University
- Institute of Cell and Neurobiology, Charit – Universit tsmedizin
- V. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
- M. Lomonosov Moscow State University
- 期: 卷 23, 编号 1 (2020)
- 页面: 27-34
- 栏目: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/1028-7221/article/view/119350
- DOI: https://doi.org/10.46235/1028-7221-003-NSO
- ID: 119350
如何引用文章
全文:
详细
作者简介
I. Astrakhantseva
Scientific and Technological University “Sirius”;N. Lobachevsky State University
Email: fake@neicon.ru
Astrakhantseva I.V., PhD (Biology), Senior Research Associate 俄罗斯联邦
L. Gladkova
N. Lobachevsky State University
Email: fake@neicon.ru
Gladkova L.S., Laboratory Assistant 俄罗斯联邦
E. Vasilenko
N. Lobachevsky State University
Email: fake@neicon.ru
Vasilenko E.A., Lecturer 俄罗斯联邦
V. Tarabykin
N. Lobachevsky State University;Institute of Cell and Neurobiology, Charit – Universit tsmedizin
Email: fake@neicon.ru
Tarabykin V.S., PhD, MD (Biology), Professor, Head, Brain Development Genetics Laboratory Institute of Biology and Biomedicine
Director
俄罗斯联邦M. Drutskaya
V. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Email: fake@neicon.ru
Drutskaya M.S., PhD (Biology), Leading Research Associate 俄罗斯联邦
S. Nedospasov
Scientific and Technological University “Sirius”;V. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences;
M. Lomonosov Moscow State University
编辑信件的主要联系方式.
Email: sergei.nedospasov@gmail.com
Nedospasov S.A., PhD, MD (Biology), Professor, Full Member, Russian Academy of Sciences, Head, Laboratory of Molecular Mechanisms of Immunity
Head, Department of Immunology, Faculty of Biology
Head, Department
俄罗斯联邦参考
- Астраханцева И.В., Василенко Е.А., Бабаев А.А., Губернаторова Е.О., Горшкова Е.А., Друцкая М.С., Круть В.Г., Тарабыкин В.С., Недоспасов С.А. Поиск генов, связанных с развитием септического шока, методами прямой генетики // Российский иммунологический журнал, 2018. Т. 12, № 4. С. 55-61.
- Борисова Е.В., Епифанова Е.А., Тутукова С.А., Белоусова И.И., Жидкова Н.М., Русанова А.М., Салина В.А., Туровский Е.А., Туровская М.В., Tarabykin V.S., Бабаев А.А. Идентификация новых генетических мутаций, контролирующих пороки развития коры головного мозга, вызванных посредством ENUиндуцированного мутагенеза у мышей // Современные технологии в медицине, 2018. Т. 10, № 3. С. 70- 77.
- Корнеев К.В. Мышиные модели сепсиса и септического шока // Молекулярная биология, 2019. Т. 53, № 5. С. 1-16.
- Beutler B., Kruys V. Lipopolysaccharide signal transduction, regulation of tumor necrosis factor biosynthesis, and signaling by tumor necrosis factor itself. J. Cardiovasc. Pharmacol., 1995, Vol. 25, Suppl. 2, pp. 1-8.
- Beutler B., Milsark I.W., Cerami A.C. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science, 1985, Vol. 229, no. 4716, pp. 869-871.
- Bull K.R., Rimmer A.J., Siggs O.M., Miosge L.A., Roots C.M., Enders A. Unlocking the bottleneck in forward genetics using whole-genome sequencing and identity by descent to isolate causative mutations. PLoS Genet., 2013, Vol. 9, no. 1, e1003219. doi: 10.1371/journal.pgen.1003219.
- Caignard G., Eva M.M., van Bruggen R., Eveleigh R., Bourque G., Malo D., Gros P., Vidal S.M. Mouse ENU mutagenesis to understand immunity to infection: methods, selected examples, and perspectives. Genes (Basel), 2014, Vol. 29, 5, no. 4, pp. 887-925.
- Cashman S., Lampe K., Sheridan R., Hoebe K. An ENU mutagenesis approach to dissect “self ”-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology, 2012, Vol. 1, 1, no. 6, pp. 856-862.
- Cavaillon J.-M. Exotoxins and endotoxins: Inducers of inflammatory cytokines. Toxicon., 2018, Vol. 149, pp. 45-53.
- Erickson R.P., Mitchison N.A. The low frequency of recessive disease: insights from ENU mutagenesis, severity of disease phenotype, GWAS associations, and demography: an analytical review. J. Appl. Genet., 2014, Vol. 55, no. 3, pp. 319-327.
- Freudenberg M.A., Keppler D., Galanos C. Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect. Immun., 1986, Vol. 51, no. 3, pp. 891-895.
- Galanos C., Freudenberg M.A. Mechanisms of endotoxin shock and endotoxin hypersensitivity. Immunobiology., 1993, Vol. 187, no. 3-5, pp. 346-356.
- Kinoshita M., Miyazaki H., Nakashima H., Nakashima M., Nishikawa M., Ishikiriyama T. In vivo lipopolysaccharide tolerance recruits CD11b+ macrophages to the liver with enhanced bactericidal activity and low tumor necrosis factor-releasing capability, resulting in drastic resistance to lethal septicemia. J. Innate. Immun., 2017, Vol. 9, no. 5, pp. 493-510.
- Kuhla A., Eipel C., Siebert N., Abshagen K., Menger M.D., Vollmar B. Hepatocellular apoptosis is mediated by TNFalpha-dependent Fas/FasLigand cytotoxicity in a murine model of acute liver failure. Apoptosis., 2008, Vol. 13, no. 12, pp. 1427-38.
- Luan H.H., Wang A., Hilliard B.K., Carvalho F., Rosen C.E., Ahasic A.M., Herzog E.L., Kang I., Pisani M.A., Yu S., Zhang C., Ring A.M., Young L.H., Medzhitov R. GDF15 is an inflammation-induced central mediator of tissue tolerance. Cell, 2019, Vol. 178, no. 5, pp. 1231-1244.e11.
- Poltorak A., He X., Smirnova I., Liu M.-Y., van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science, 1998, Vol. 282, no. 5396, pp. 2085-2088.
- Rietschel E.T., Kirikae T., Schade F.U., Mamat U., Schmidt G., Loppnow H., et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J., 1994, Vol. 8, no. 2, pp. 217-225.
- Shakhov A.N., Collart M.A., Vassalli P., Nedospasov S.A., Jongeneel C.V. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J. Exp. Med., 1990, Vol. 171, no. 1, pp. 35-47.
- Stottmann R., Beier D. ENU mutagenesis in the mouse. Curr. Protoc. Hum. Genet., 2014, Vol. 82, 15.4.1-10. doi: 10.1002/0471142905.hg1504s82.