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The Effect of Heavy Ion Irradiation on the Metabolism of Technologically and Biologically Significant Microorganisms: Biotechnological Prospects of Application

Мұқаба

Дәйексөз келтіру

Толық мәтін

Аннотация

Purpose: To review the literature on the use of heavy ion beam mutagenesis for selecting various microorganisms, including bacteria, fungi, yeast, and microalgae, for biotechnological purposes.

Material and methods: Data have been collected over the past 15 years on the metabolic effects of mutants exposed to heavy ions, biotechnologically significant microbiological objects (bacteria, fungi, algae).

Results and discussion: The biotechnological and genetic significance, as well as the morphological and other aspects of the detected changes in mutant microbiological objects, are discussed. Currently, heavy ion irradiation-induced mutagenesis with high linear energy transfer and biological efficiency is recognized as a powerful new method for creating microbial strains with previously unknown properties. We believe that targeted breeding using heavy ion mutagenesis will make a significant contribution to the development of industrial producer strains for biotechnology.

Conclusion: The studies discussed in this review indicate that the use of ion beam mutagenesis for microorganisms can be beneficial for both fundamental science and applied research.

Авторлар туралы

A. Gutnov

North Ossetian State University

Email: gutnov@mail.ru
Vladikavkaz, Russia

O. Belov

Joint Institute for Nuclear Research

Email: gutnov@mail.ru
Dubna, Russia

G. Kachmazov

North Ossetian State University

Email: gutnov@mail.ru
Vladikavkaz, Russia

T. Magkoev

North Ossetian State University

Email: gutnov@mail.ru
Vladikavkaz, Russia

N. Popova

Institute of Theoretical and Experimental Biophysics

Email: gutnov@mail.ru
Pushchino, Russia

N. Pukhaeva

North Ossetian State University; Joint Institute for Nuclear Research

Email: gutnov@mail.ru
Vladikavkaz, Russia; Dubna, Russia

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