Innovative drugs: From basic research to production

Аннотация

The results of studies of the molecular action mechanism of the peptides Semax and Selank—simple glyprolines that are used to prepare peptide-based drugs—are presented. A concept of creating an amino acid sequence of peptides is given; their interaction with receptor systems of the cell and their influence on the cell’s transcriptome, which forms the cell-mediated response, are considered. On the basis of the findings, pharmaceutical compositions of peptide drugs have been developed and their production and introduction into clinical practice have been organized.